A rhodamine based near-infrared fluorescent probe for selective detection of Cu ions and its applications in bioimaging.

A novel near-infrared fluorescent probe TM2 based on a rhodamine-bearing framework was disclosed with a large Stokes shift (100 nm). TM2 exhibits highly selective recognition for Cu in EtOH/HO (1 : 1, v/v) solution with a low detection limit (2.3 μM) and a wide detection range (0-50 μM).

A Novel Micro-Contact Stiffness Model for the Grinding Surfaces of Steel Materials Based on Cosine Curve-Shaped Asperities.

Contact stiffness is an important parameter for describing the contact behavior of rough surfaces. In this study, to more accurately describe the contact stiffness between grinding surfaces of steel materials, a novel microcontact stiffness model is proposed. In this model, the novel cosine curve-shaped asperity and the conventional Gauss distribution are used to develop a simulated rough surface.

Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B production.

Propofol is an intravenous anesthetic that produces its anesthetic effect, largely the GABA receptor in the CNS, and also reduces the -formyl-methionyl-leucyl-phenylalanine (fMLP)-induced neutrophil respiratory burst. Because fMLP-stimulated neutrophils produce leukotriene (LT)B, we examined the effect of propofol on LTB production and Cecal ligation and puncture surgery was performed in mice, with or without exposure to propofol. Propofol attenuated the production of 5-lipoxygenase (5-LOX)-related arachidonic acid (AA) derivatives in the peritoneal fluid.