Antifungal activity of paeonol against by disrupting the cell membrane and the application on cherry tomato preservation.

may cause gray mold in fruits and vegetables. Paeonol, an active component of traditional Chinese medicine, could suppress various microbial growth. However, reports on its effect on have not yet been documented.

Transcriptomic analysis reveals that Bacillomycin D-C16 induces multiple pathways of disease resistance in cherry tomato.

Background: Bacillomycin D-C16 can induce resistance in cherry tomato against pathogens; however, the underlying molecular mechanism is poorly understood. Here, the effect of Bacillomycin D-C16 on induction of disease resistance in cherry tomato was investigated using a transcriptomic analysis.

Results: Transcriptomic analysis revealed a series of obvious enrichment pathways.

Identification and antibiotic resistance of Cronobacter spp. isolated from dried edible mushrooms.

Cronobacter spp. is an important foodborne pathogen that can cause life-threatening diseases in infants and immunocompromised adults. The present study was carried out to understand the prevalence and characterization of Cronobacter spp.

Bacillomycin D-C16 inhibits growth of Fusarium verticillioides and production of fumonisin B in maize kernels.

Fusarium verticillioides causes ear and kernel rot in maize and produces mycotoxins, like fumonisin B (FB). Bacillomycin D-C16 is a natural antimicrobial lipopeptide produced by Bacillus subtilis. In this study, the inhibitory effects of Bacillomycin D-C16 on the growth of F.

Iturin A Induces Resistance and Improves the Quality and Safety of Harvested Cherry Tomato.

The soft rot disease caused by is an important disease in cherry tomato fruit. In this study, the effect of iturin A on soft rot of cherry tomato and its influence on the storage quality of cherry tomato fruit were investigated. The results showed that 512 μg/mL of iturin A could effectively inhibit the incidence of soft rot of cherry tomato fruit.

An exopolysaccharide from Lactobacillus plantarum H31 in pickled cabbage inhibits pancreas α-amylase and regulating metabolic markers in HepG2 cells by AMPK/PI3K/Akt pathway.

In this study, we investigated the structural characterization and antidiabetic effects of Lactobacillus H31 exopolysaccharide (EPS) H31-2 from pickled cabbage. The BLAST result indicated that Lactobacillus H31 was closely related to Lactobacillusplantarum S1S2L2. In the spectrum of Fourier-transform infrared spectroscopy (FT-IR), 3370 cm was the characteristic band of polysaccharide.

Resistance mechanisms adopted by a Salmonella Typhimurium mutant against bacteriophage.

Bacteriophages have key roles in regulating bacterial populations in most habitats. A Salmonella Typhimurium mutant (N18) with impaired sensitivity to phage fmb-p1 was obtained and examined, the adsorption efficiency of fmb-p1 to N18 was reduced to 6%, compared to more than 97% for wild type S. Typhimurium CMCC50115.

Bacillomycin D inhibits growth of Rhizopus stolonifer and induces defense-related mechanism in cherry tomato.

The inhibitory effect of Bacillomycin D, a cyclic lipopeptide, on Rhizopus stolonifer colonization of cherry tomato was studied, and its possible mechanism of action was explored. Bacillomycin D showed a direct inhibitory effect on R. stolonifer spore germination and mycelial growth in vitro.

Bacillomycin D-C16 triggers apoptosis of gastric cancer cells through the PI3K/Akt and FoxO3a signaling pathways.

Bacillomycin D can inhibit the growth of Aspergillus ochraceus in food samples. In addition, it can induce apoptosis in and inhibit the proliferation of cancer cells, although the details of this mechanism are unknown. In this study, we separated bacillomycin D-C14, D-C15, D-C16 monomers from the Bacillus subtilis strain fmbJ.

Chitosan-based core-shell structured particles for in vivo sustainable gene transfection.

A core-shell structured chitosan (CS)-based gene vector with a sustainable gene transfection effect was designed and successfully prepared in this study. The pEGFP was first combined with the thiolated and N-alkylated chitosan (TACS). Then, hydroxybutyl chitosan grafted with poly(ethylene glycol) (EG-HBC) was coated on the pEGFP-loaded TACS particles.

The preparation, drug loading and in vitro NIR photothermal-controlled release behavior of raspberry-like hollow polypyrrole microspheres.

The combination of NIR photothermal therapy and chemotherapy is considered as the promising technique for future cancer therapy. The key point of this technique is the design and synthesis of photothermal agents with high-efficiency photothermal effects and high chemical drug loading capacity. Herein, submicron-sized raspberry-like hollow-structured polypyrrole microspheres (H-PPy) were facilely prepared through in situ polymerization of pyrrole on monodispersed polystyrene (PS) template microspheres with a diameter of 220 nm, followed by the chemical etching of PS templates.

The sustained-release behavior and in vitro and in vivo transfection of pEGFP-loaded core-shell-structured chitosan-based composite particles.

Novel submicron core-shell-structured chitosan-based composite particles encapsulated with enhanced green fluorescent protein plasmids (pEGFP) were prepared by complex coacervation method. The core was pEGFP-loaded thiolated N-alkylated chitosan (TACS) and the shell was pH- and temperature-responsive hydroxybutyl chitosan (HBC). pEGFP-loaded TACS-HBC composite particles were spherical, and had a mean diameter of approximately 120 nm, as measured by transmission electron microscopy and particle size analyzer.