Publications by authors named "Fuxia Wei"

Article Synopsis
  • Polysaccharide from Ephedra sinica (ESP) shows strong therapeutic effects on rheumatoid arthritis (RA) by reducing inflammation and protecting cartilage in a mouse model of collagen-induced arthritis (CIA).
  • Treatment with ESP decreases levels of pro-inflammatory cytokines and enhances the integrity of the intestinal mucosal barrier while also altering gut microbiota and associated enzymes.
  • Findings from this research suggest that ESP influences both immune response pathways and metabolic profiles in CIA mice, indicating potential mechanisms for its anti-inflammatory effects in RA.
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Metastases and drug resistance are the major risk factors associated with breast cancer (BC), which is the most common type of tumor affecting females. Icariin (ICA) is a traditional Chinese medicine compound that possesses significant anticancer properties. Long non-coding RNAs (lncRNAs) are involved in a wide variety of biological and pathological processes and have been shown to modulate the effectiveness of certain drugs in cancer.

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Inflammatory bowel disease is a disease that can invade the whole digestive tract and is accompanied by immune abnormalities. Immune dysfunction involving dendritic cells (DCs) and T cells is recognized as a key factor in diseases. Indirubin (IDRB) exerts antiinflammatory effects and can help in treating immune diseases.

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Objective: Inflammatory bowel disease (IBD) is a chronic nonspecific inflammatory bowel disease with an unclear etiology. The active ingredients of traditional Chinese medicines (TCMs) exert anti-inflammatory, antitumor, and immunomodulatory effects, and their multitarget characteristics provide them with a unique advantage for treating IBD. However, the therapeutic effects and underlying mechanisms of Xi Lei San in treatment of IBD remain unknown.

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