Scrotal cancer: deja vu.

Carcinoma of the scrotum is a rare disease. Two recent cases are briefly described and the condition reviewed from a historical perspective. Case 1: A 55 year old man on minimal doses of immunosuppressives 10 years after renal transplantation developed 2 squamous cell carcinomas, one on the forehead, the other and larger was a 1.

Increased prevalence and analysis of risk factors for indinavir nephrolithiasis.

Purpose: Indinavir is a protease inhibitor used for treating HIV-1. The drug is lithogenic and was thought to cause a 3% incidence of kidney stones. We evaluated a cohort of patients positive for HIV on indinavir to determine the incidence of indinavir nephrolithiasis and identify risk factors for indinavir stone formation.

Diagnosis of renal malacoplakia by fine needle aspiration cytology. A case report.

Background: Malacoplakia is a rare chronic inflammatory disease first described by von Hansemann in 1901. L. Michaelis and M.

Iatrogenic ureteric injuries: approaches to etiology and management.

Injury to the ureter is a risk of any pelvic or abdominal surgery, including laparoscopy and ureteroscopy. The morbidity associated with such injury may be serious, resulting in increased hospital stay, compromise of the original surgical outcome, secondary invasive interventions, reoperation, potential loss of renal function and deterioration of the patient's quality of life. Management of ureteric injuries, in conjunction with frank and open dialogue with the patient, can lead to an optimal outcome.

[Treatment of cancer of the bladder in elderly patients with an intra-arterial chemotherapy and radiotherapy combination: 10-year experience].

Purpose: Analysis of the results obtained in elderly (75 years and older) included a phase II trial combining intra-arterial cisplatin and concurrent radiation into invasive bladder cancer.

Patients And Methods: Thirty-five patients (28 males and 7 females) were accrued from 1985 to 1996. There were 1 Ta, 4 T2, 11 T3A, 12 T3B, 3 T4A, and 4 T4B patients.

Effect of pelvic radiotherapy for prostate cancer on bowel, bladder, and sexual function: the patient's perspective.

Objectives: To document the effects of pelvic radiotherapy on bowel, bladder, and sexual function, as reported by the patient.

Methods: A confidential questionnaire was distributed to 202 prostate cancer patients. Mean age was 70 years (range, 49 to 87) and mean follow-up was 33 months (range, 12 to 72).

Interstitial brachytherapy for penile carcinoma: an alternative to amputation.

From 1987 to 1994, 15 patients with penile saquamous cell carcinoma were referred to the Ottawa Regional Cancer Centre. Seven had already been managed surgically. The other eight were treated with interstitial implantation.

A vesicouterine fistula caused by catheterization during delivery.

We report a case of a vesicouterine fistula occurring after catheterization during delivery in a women who had two previous Caesarian sections. Fistulae between the bladder and uterus are rare; they have been reported after prolonged and neglected labor 1 and after caesarian section. 2 This case followed catheter penetration of the bladder and thinned cervix during delivery.

Renal cell carcinoma: incidental detection.

The mode of presentation of renal cell carcinoma is changing; in 40% of cases the condition is now found incidentally during the investigation of complaints other than those usually associated with this tumour. Chemotherapy and radiotherapy have not improved the survival of patients with renal cell carcinomas, but, with the introduction of ultrasonography, renal cell carcinomas, including those found incidentally, are being diagnosed earlier than they were a decade ago, resulting in improved survival rates.

Phase I and pharmacology study of intravesical mitoxantrone for recurrent superficial bladder tumors.

A phase 1 study of intravesical mitoxantrone was done in patients with superficial bladder tumors recurrent after previous intravesical therapy. Mitoxantrone (5 to 10.5 mg.

Intraarterial cisplatin and concurrent radiation for locally advanced bladder cancer.

Between 1983 and 1987 25 patients with invasive bladder cancer (16 stage tumor 3 (T3) and nine stage T4) were treated with intraarterial cisplatin and concurrent radical radiation (20/25) or intraarterial cisplatin, concurrent preoperative radiation, and cystectomy (5/25). One patient died from treatment-related toxicity. Other toxicities have been what one would expect from the individual treatment modalities except for a sensory sacral root neuropathy in 11 of 24 (46%) patients.

Mitomycin-C and metronidazole in the treatment of advanced renal-cell carcinoma.

Fifteen patients with advanced renal-cell carcinoma were treated with the combination of mitomycin-C 14-20 mg/m2 i.v. every 7 weeks and metronidazole 1,500 mg/m2 p.

Intra-arterial cisplatin for bladder cancer.

Cisplatin (25 to 120 mg. per m.2) was injected into the internal iliac arteries of 33 patients with locally advanced bladder cancer.

Inverted Y duplication of the ureter.

We report a case of inverted Y duplication of the ureter associated with an ectopic ureterocele.

Intra-arterial cisplatin treatment of unresectable or medically inoperable invasive carcinoma of the bladder.

Five patients between 72 and 82 years old received 5 to 6 treatments of 50 to 75 mg. per m.2 cisplatin by bilateral internal iliac artery infusion for unirradiated invasive transitional cell carcinoma of the bladder.

The role of gonadal venography in the management of the adult with non-palpable undescended testis.

Selective gonadal venography was performed on 9 adult patients with 11 nonpalpable undescended testes. The gonad was accurately localised pre-operatively on 7 occasions. Testicular agenesis was predicted in 2 instances and strongly suggested in 2 others.

Inaccuracies in angiographic staging of renal cell carcinoma.

In 54 patients with renal cell carcinoma, the angiographic T category of the International Union Against Cancer (UICC) clasification correlated with the histopathologic (P) staging in only 44.4 per cent. Staging of the primary lesion in renal cell carcinoma must be based on the P category and not the angiographic appearances.