[Research of the durability of connective tissue complexes formed in the implantation area of various types of allograft during the experiment].

The aim of the study is to examine in the experiment on the animals the mechanical properties of connective tissue complexes formed in alloplasty area using the intraperitoneal on lay mesh and sublay methodologies with further comparison of them. The experiment has been conducted on 12 rabbits of Russian chinchilla breed. Animals were distributed in the following way: the first group--operated by intraperitoneal on lay mesh methodology (n = 6) through implantation of composite grid Proceed with one-side celullose coating produced by "Ethicon" company.

[Investigation of adhesive properties of polypropylene net prosthesis "ESPERA"].

Adhesive towards the cells properties of three polypropylene net prostheses (PNP), manufactured by "Espera", with the slots size 1 x 1 mm, 2 x 2 mm, 2 x 4 mm and one specimen (the slot diameter 1 mm) on the oxycellulose background, were tested for prognostication of hernioplasty results, using nonresorbable PNP. The adhesion degree and peculiarities of cellular line, obtained from embryonal kidney of pig, put on the tested nets specimen in conditions of cultivation during 5 - 10 days were estimated, using inverted microscope in regime of phasic contrast. The data obtained witness the lowered cellular adhesion towards PNP "Espera" without oxycellular background.

[Classification of a high temperature methods for tissue dissection and achievement of hemostasis].

The results of experimental-clinical investigation, using apparatuses of a highly-temperature dissection and coagulation of a various type of action, were adduced. Classification of a highly-temperature dissection and coagulation in accordance to type of action and kind of the energy used was elaborated, basing on analysis of results of experimental operations and clinical application of apparatuses of various manufactures.

[Practical application of a high-frequency coagulators with different electrophysical characteristics].

The results of experimental-clinical investigation on studying of technical characteristics and practical application of various types of electrocoagulators were adduced. Comparative analysis of possibility to perform the main stages of surgical interventions, using well-known apparatuses of various manufacturers, was conducted.

[Creation of models of incomplete external lip-like large bowel fistula in experiment].

The method of experimental simulation of the incomplete external lip-like large bowel fistula creation was elaborated on experimental animals for studying of possibilities forapplication of hyperthermic methods of the fistula channel obliteration and disinfectioning of the neighboring anterior abdominal wall tissues. There were studied up microflora and bacterial seeding of the large bowel contents in the zone of a fistula exit as well as dynamics of changes of inflammatory processes, occurring in tissues of anterior abdominal wall, neighboring the external orifice of a fistula channel.

[Experimental investigations of coagulation possibilities of noncoherent optico-electronic systems in operations on parenchymatous organs].

Results of experimental investigation on elaboration and trial of surgical hemostasis method, using the quartz heating optic noncoherent irradiators of light, are adduced. Basing on analysis of the results obtained, the apparatus for photooptic coagulation was elaborated and trialed on experimental animals.

[Investigation of the method of electric welding of organs and tissues on the models of clinical operations in experiment].

A new method of sutureless connection of tissues during surgical procedures was developed. Potentialities of the method of electric welding of biological tissues in abdominal surgery are studied. For this purpose an investigation of regeneration processes in the area of using electric welding on the large intestine as well as the liver under conditions of intact tissues and against the background of hyperglycemia and atherosclerosis model was performed.

[Synthetic materials used in surgery and their transformation in organism].

Our experience of elaboration and introduction of various synthetic materials proves trustworthily the necessity of conduction of a long-term complex investigations by various scientific centers with the objective of creation and application in Ukrainian surgical practice a medical materials of own production as accessible, safe and qualitative preparations. And more, the Ukraine may implement such programs, taking into account a great scientific-technical power she owes.

[Experimental aprobation of the thermo-squirt method of treatment of infected and purulent wounds of the soft tissues].

The influence of thermo-squirt processing on sanation of infected and purulent wounds of soft tissues was investigated in experiment. The possibility of application of the elaborated method for the wound surface disinfection and the tissues healing processes stimulation was proved.

[Using hypertermal methods in spleen resection in experiment].

Experimental study of hyperthermal methods usage in spleen-saving surgery are presented. Means of plasmic and thermal flow spleen resection, which were proven to be effective and reliable were developed. Comparative analysis of different method application has shown equatable results for hyperthermal methods and their advantage over sutural and gluing methods.

[Development of simulation model of nonparasitic hepatic cyst treatment in experiment].

The experiment was divided on two stages. On the first stage there was planned elaboration of the hepatic nonparasitic cyst (HNPC) model, on the second--application of various methods of processing of the cyst residual cavity to estimate its eficacy and traumaticity. After elaboration of experimental model of HNPC the white rats were excluded from the experiment on the 3, 7, 14, 21, 60, 90th and 180th day.

[Comparative characteristics of methods for the hepatic tissue conjunction in its wedge-like resection].

As a result of investigation for accessible and secure method for the biotissues conjunction, using physical facilities, the plasma and thermoflow welding was developed, efficacy of which was confirmed doing comparative analysis of data, obtained while applying the adhesive and suture methods.

[Technical peculiarities of the argon-plasma welding of gastrointestinal walls wounds in experimental environment].

A new method of the live biological tissues connection, using thermal energy of a high-temperature argon plasma, constituting perspective trend of application of a new nonsuture methods of the tissues connection, original for the world practice, was elaborated in the Department of Experimental Surgery together with the Institute of welding named after Academician E. O. Paton NAS of Ukraine.

[The plasm welding of the digestive system organs in experiment].

The plasm welding of the gut organs--perspective trend, which permits to increase the surgeon possibilities in performance of operative intervention. The results of operations, performed on large intestine and stomach, trusts, that it is possible to apply the streams of the high temperature gas plasm for the tissues dissection and connection. There are such advantages of the method, as the operation time shortage, simplicity in manipulating "Plasmomed" apparatus, absence of foreign bodies in the connection zone, high degree of hemostasis achieved.

[Experimental substantiation of the method of biological tissue welding in surgical hepatology].

Application of the welding method for biological tissues in hepatobiliary surgery was experimentally substantiated. In 14 pigs (25-30 kg body mass) resection of one hepatic lobe, using electric welding method, was done. In control group (4 pigs) the similar operative intervention was accomplished, using conventional method.

[Experimental application of electrocautery in biliary surgery].

The testing of a new nonsuture electrothermic method of biliary system tissues connection was conducted in laboratory animals--rabbits and pigs. Reactions of tissues and cells in zone of electric influence and the gallbladder suture, remote reactive changes in the operation zone were studied up. In application of the proposed method of the regeneration processes inhibition and specific pathological changes in surrounding tissues were not noted, speed of the damage structure restoration was comparable with such in the tissues connection using suture materials.

[Experimental elaboration and perspectives of application of electric welding of the live tissues].

In experiment on pigs, rabbits and white rats there was examined method of electric welding (electrothermoadhesion) of live tissues--intestine, stomach, gallbladder and bladder, peritoneum, elements of mesentery, liver, spleen. We distinguish among "welding" of the hollow organs wall with restoration of their passability and "overwelding" of masses of the tissues with production of coagulational furrow, along which resection of necessary parts is executed. According to data of morphological investigations obtained the security of the method was established.

[The formation of large intestine anastomoses by experimental electrothermal adhesion].

The method of colonic anastomoses formation by the tissues conjunction using alternating electric current (electric welding) was proposed. The procedure of the anastomosis formation in experiment is adduced.