Pathogen Detection in Ticks and Invasive House Mice in Senegal.

() ticks are the only known vectors of , an agent of tick-borne relapsing fever (TBRF) borreliosis. Rodents serve as principal natural reservoirs for . Our research objective was to detect TBRF and other zoonotic bacterial infections in ticks and in house mice , an invasive species currently expanding in rural northern Senegal.

From Human Geography to Biological Invasions: The Black Rat Distribution in the Changing Southeastern of Senegal.

In the contemporary context of zoonosis emergence and spread, invasive species are a major issue since they represent potential pathogen hosts. Even though many progresses have been done to understand and predict spatial patterns of invasive species, the challenge to identify the underlying determinants of their distribution remains a central question in invasion biology. This is particularly exacerbated in the case of commensal species that strictly depend on humankind for dispersal and perennial establishment of new populations.

[Breast cancer in Finistère, France: epidemiological description and tendencies over a 10-year period (2000-2009) according to pathology data].

Unlabelled: The aim of this study was the description of breast carcinoma over a 10-year period according to pathology data.

Method: Descriptive epidemiological study based on data collection of pathological code ADICAP (injury, organ, and applied technical), histological, hormonal, node and administrative data. From January 1st 2000 to December 31st 2009, 6186 women living in Finistère have had a diagnosis of invasive breast carcinoma.

[Bi-symptomatic CINCA syndrome with inaugural urticaria and major articular lesions].

Background: CINCA syndrome (chronic infantile neurological cutaneous and articular syndrome) observed in young children associates chronic urticaria and rheumatological disorders which may cause deformation of the larger peripheral joints. Neurological signs develop later leading to severe prognosis: chronic meningitis, deafness, mental retardation. We present a bisymptomatic case which was distinctive by the absence of central nervous system involvement after 11 years of course.

Shaving: a simple and effective treatment for moderate congenital hypertrichosis.

Congenital hypertrichosis is a rare disorder. It is sometimes associated with facial dysmorphism, and dental and gingival abnormalities. This condition constitutes an esthetic problem and regular shaving with a simple razor can be a simple method of treatment.

[Focalized multiple beam radiotherapy: an alternative in the treatment of deep cerebral arteriovenous malformations].

Background: Cerebral arteriovenous malformations are usually treated by excision or selective embolization. Some untreatable malformations may be presently cured by radiosurgery.

Case Report: A 10-year-old girl without previous illness suffered from a sudden quadriventricular hemorrhage due to arteriovenous malformation.

Primary cutaneous nocardiosis caused by Nocardia otitidiscaviarum: two cases and a review of the literature.

We report two cases of primary cutaneous nocardiosis due to Nocardia otitidiscaviarum. The first case is a mycetoma, the second, a cutaneous abcess: these two cases were imported into France (Vietnam, Zimbabwe). The literature on primary cutaneous nocardiosis due to N.

[Multiple basocellular epitheliomas of the back after repeated radiologic tests].

The authors report the observation of multiple epitheliomas of the back in a patient submitted to numerous radiological examination forty years earlier. They recall the likely risk of the appearance of these cutaneous tumours after this type of exposure.

[Adrenoleukodystrophy in the child and adrenomyeloneuropathy. Study of 2 families].

Ten subjects from 2 families with adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN), hereditary X-linked diseases, were systematically explored. We performed endocrinological, biochemical assays and neurophysiological tests; the latter consisted of nerve conductions (CNV), Hoffmann's reflex and multimodal evoked potentials: visual (flash and pattern, VEP), brainstem auditory (BAEP) and somesthetic (SEP) using median nerve stimulation at the wrist. We only considered values above 2 SD.

[Suspicion of Haemophilus influenzae endocarditis of the bicuspid aortic valve in a 7-month-old infant].

The authors report a case of probable Haemophilus influenzae endocarditis in a 7 month-old infant with a bicuspid aortic valve. Precocity of the occurrence of endocarditis in such asymptomatic cardiac abnormality, scarcity of the suspected germ, and the observed mode of evolution are underlined. This case raises the problem of an endocardial involvement in an infant properly treated by adapted intravenous antibiotherapy.

[The value of echography in the early diagnosis of renal lesions in the Laurence-Moon-Bardet-Biedl syndrome. Apropos of a case].

The Laurence-Moon-Bardet-Biedl syndrome (LMBB) is characterized by the association of obesity, hypogonadism, polydactyly, mental retardation and pigmentary retinitis. Symptomatic or asymptomatic renal dysplasia (calyceal diverticula, precalyceal tubular ectasia, cysts) is frequently associated with LMBB. The authors consider renal sonography as the convenient investigation for an early detection of such dysplasia as in the case they reported here.

[Systemic scleroderma in children].

A new case of systemic scleroderma in a child is reported. The frequency of this disease is much lower than focal scleroderma and than other connective diseases in childhood. Kidney and heart involvement is much less common than in adults.

[Apropos of a familial case of adrenoleukodystrophy related to X chromosome diagnosed prenatally].

The juvenile type of adrenoleukodystrophy is a X linked genetic disorder involving the central nervous system and the adrenal cortex. It is associated with an abnormal metabolism of saturated very long chain fatty acids. The basic defect remains unknown and there is presently no effective treatment.

[Familial adrenoleukodystrophy].

Adrenoleucodystrophy (ALD) is an X-linked hereditary disease concerning very long chain fatty acid (VLCFA) metabolism. It affects cerebral white matter and adrenal cortex. In the adult form, (adrenomyeloneuropathy) we also find hypogonadism.

Metabolic pathway by cleavage of a furan ring.

14C-Diclofurime, a new Ca antagonist, was administered orally to dogs and pigs, and metabolites detected in urine and plasma. Metabolites contained in pooled urine were concentrated by column chromatography (reverse phase, gel permeation and normal phase). Chemical structures were determined by i.

[Infant encephalopathies with rapid EEG rhythms. Apropos of 2 cases].

The authors report two cases of infant encephalopathies with psychomotor retardation. The cerebrospinal fluid, the electroretinogram, the electromyogram and the motor conduction velocity are normal. The neuromuscular cutaneous conjunctival biopsies are normal.

[Hormonal profile and HLA typing of adult subjects from 7 families with congenital adrenal hyperplasia caused by 21-hydroxylase deficiency].

Most members of seven families in whom one subject was known to have congenital adrenal hyperplasia due to 21-hydroxylase deficiency were haplotyped for HLA B antigen which was supposed to be linked to the defective gene. Heterozygous males (group 1, n = 9), and females (group 3, n = 8) were recognized. These had no clinical abnormalities.

[Autochtonous kala-azar (author's transl)].

Kala-Azar or visceral "leishmanisis" is a Mediterranean parasitosis. Outside this area, the reported cases concern children having lived in an endemic area. Real autochtonous Kala-Azar is really exceptional in France.

[Accidental localized vaccinia. A report of six recent cases (author's transl)].

Vaccination against smallpox should be discontinued in all countries except for individuals with a high risk of exposure (WHO, 1980). Since this vaccination is performed less and less often, one must expect complications to occur, the etiology of which may not be recognized. This course of events leads the authors to point out the difficulties in diagnosis and therapy of localized accidental vaccinia encountered in six patients hospitalized in Brest (1971-1979).

Spontaneous spinal epidural hematoma in a 22-month-old girl.

The authors report the case of a 22-month-old girl who developed cervical pain, neck stiffness, and quadriparesis over 12 days. An epidural hematoma was removed, with complete recovery after 6 months. There was no history of trauma.