Publications by authors named "Funmilola O Wuraola"

Article Synopsis
  • In Nigeria, gastric cancer ranks as the 10th most common and 9th most deadly cancer, but there is limited data available to fully understand it.
  • A study evaluated 138 patients diagnosed with gastric cancer over 15 years, finding that most patients presented with significant weight loss and anorexia, and many had advanced disease.
  • Most patients received some form of treatment, with nearly half undergoing both chemotherapy and surgery, though over 50% were deceased by the time of follow-up, highlighting the need for improved data quality and timely interventions.
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Article Synopsis
  • - The study examines out-of-pocket costs for breast cancer treatment in Nigeria, highlighting that most patients face significant financial burdens, with a majority experiencing catastrophic health expenditures (CHE) due to the high costs of care.
  • - Data was gathered from 71 patients undergoing treatment, revealing that 78.9% to 100% experienced CHE, as their healthcare costs often exceeded 40% of their ability to pay or set income thresholds, and most patients lacked health insurance.
  • - The findings underscore the urgent need for policy changes to improve access to affordable cancer care in Nigeria, given that over 70% of patients at a major facility are financially strained by their treatment.
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Purpose: The incidence of GI cancers is increasing in sub-Saharan African countries. We described the oncological care pathway and assessed presentation, diagnosis, and treatment intervals and delays among patients with GI cancer who presented to the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife, Nigeria.

Methods: We analyzed data from 545 patients with GI cancer in the African Research Group for Oncology (ARGO) database.

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  • Breast cancer is the most common cancer in women globally, and this review investigates the effectiveness of oncoplastic breast-conserving surgery (OBCS) among African women, comparing cosmetic and oncologic outcomes to those found in developed countries.
  • The review analyzed 26 studies involving 1,896 patients from mainly Egypt and South Africa, revealing high satisfaction rates with cosmetic outcomes and promising survival rates of 93.1% overall and 89.4% disease-free.
  • While seroma was a common complication (44.6%), the findings suggest that OBCS in African women is effective and provides outcomes similar to those observed internationally.
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  • The study aimed to identify issues related to the safe handling and disposal of chemotherapy agents in low and middle-income countries, focusing on Nigeria.
  • Two surveys were conducted: one assessing the needs of health professionals in 2019 and another evaluating a chemotherapy facility's compliance with safety standards in 2021.
  • Results revealed significant gaps in training and satisfaction with current practices, indicating a pressing need for improved resources and strategies to ensure safe chemotherapy administration.
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Globally, cancer is the second leading cause of death, and low- and middle-income countries bear most of the disease burden. While cancer is increasingly recognized as a major global health issue, more work remains. Understanding the status of global cancer care will shape the next steps in ensuring equitable global access to cancer care.

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Background: Interest in surgical site infections (SSI) has been sustained over the years because its occurrence may be ruinous to the overall success of surgical operations. The use of antimicrobial suture has been associated with a reduction in SSI, but its role in open appendectomy has not been evaluated.

Objective: This study compared the effect of fascia closure with triclosan-coated polydioxanone (PDS) with plain PDS on SSI in appendectomy wounds.

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Background: Axillary lymph node staging is essential for making therapeutic decisions and for prognostication. A minimum of ten lymph nodes is recommended for accurate staging. This study describes the process and outcomes of an audit cycle that resulted in a novel intervention instituted to improve concordance with guidelines.

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Background: The majority of non-metastatic breast cancer patients in sub-Saharan Africa are recommended to have mastectomy. The impact of mastectomy on a predominantly young African patient population requires evaluation. The BREAST-Q is a validated patient-reported outcome measure of quality-of-life following breast surgery that has been translated into 30 languages-none in Africa.

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Article Synopsis
  • Breast cancer survivors in Nigeria represent a growing population with specific characteristics and needs, highlighting the importance of improving support and treatment outcomes.
  • Data from a breast cancer database showed that 45.9% of patients were survivors after five years, with survival linked to factors like age, stage at diagnosis, and treatment approaches.
  • Qualitative interviews revealed key themes around their experiences, emphasizing the role of strong family support and spirituality as vital coping mechanisms, while also pointing to unmet psychosocial and physical needs.
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Background: In Nigeria, breast cancer incidence is rising, late presentation is common, and outcomes are poor. Patient-related factors such as lack of awareness and misperceptions in addition to health system deficiencies such as lack of a clearly defined framework for breast cancer screening and referral are some of the major drivers of this poor outlook. Guidelines for breast cancer screening in high-income countries have limited applicability in low-middle-income countries, hence the need for innovative, resource-compatible strategies to combat the negative trend.

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  • Chemotherapy for breast cancer can lead to significant side effects, affecting treatment adherence and overall patient outcomes.
  • A study of 120 female breast cancer patients in Ibadan found that the average patient experienced 8 side effects, and 35% missed at least one chemotherapy session due to various reasons including side effects and financial issues.
  • Addressing side effects promptly may enhance patient compliance with chemotherapy and ultimately improve treatment effectiveness.
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Background: Breast cancer in the elderly population has not been evaluated in the Nigerian context. With the rising incidence of breast cancer and the changing demographics, it is likely that an increasing number of elderly patients will be managed in the coming years in Nigeria. This review describes the clinicopathological profile of elderly patients with breast cancer in a Nigerian database.

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Introduction: in Nigeria, the incidence of breast cancer has increased by over 80% in the last four decades. This study quantifies the out-of-pocket (OOP) cost of breast cancer management and the associated rate of catastrophic healthcare expenditure (CHE) at a public tertiary care facility in Ile-Ife, Nigeria.

Methods: patients treated between December 2017 - August 2018 were identified from a prospective breast cancer database.

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Introduction: Many patients who may otherwise benefit from anastomoses get a permanent colostomy for low rectal cancers in low- and middle-income countries because of lack of training and/or lack of equipment for low rectal anastomoses. Our local team provided stepwise training for stapled low rectal anastomoses.

Methods: Local surgeons with overseas formal training in colorectal surgeries facilitated periodical simulation-based training workshops on stapled low rectal anastomoses for surgeons and trainees over 3 y (2015-2017) in a Nigerian tertiary hospital.

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Background: The iBreastExam electronically palpates the breast to identify possible abnormalities. We assessed the iBreastExam performance compared with clinical breast examination for breast lesion detection in high risk and symptomatic Nigerian women.

Methods: This prospective study was done at the Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) in Nigeria.

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Background: The COVID-19 pandemic has drastically impacted postgraduate training programmes worldwide. This study aims to evaluate the Nigerian situation with respect to surgical training, with a view to identifying gaps and proffering solutions.

Methods: A cross-sectional survey of surgical residents in Nigeria was conducted between 27 July 2020 and 14 August 2020.

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Background: Undergraduate medical students of the Obafemi Awolowo University, Ile-Ife, Nigeria, had over the years acquired various skills informally without structured training in basic skills in wound closure. The Department of Surgery introduced suturing skills acquisition workshop into the curriculum of the Final-Year Medical Students in 2016. This study describes the preliminary experience and the perception of the participants.

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Purpose: The majority of women managed for breast cancer in Nigeria are relatively young, many in their forties. Mastectomy, the most common surgical treatment, raises psychosocial concerns. Understanding these concerns may help address the fears of women who refuse treatment and aid in the care of those who have had mastectomy.

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Background: Retroperitoneal hematoma (RH) can present as an acute life-threatening condition, report on RH in low-income countries are lacking.

Objective: We present the severity, pattern, challenges, and outcome of RH in a low-resource country such as Nigeria.

Methods: This was a retrospective observational study of all patients with blunt or penetrating abdominal injury needing surgery, patients with RH among them were analyzed.

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Background: Gender differences are expected to influence the pattern and outcome of management of abdominal wall hernias. Some of these are left to speculations with few published articles on hernias in females.

Objectives: To describe the clinical pattern of abdominal wall hernias in females.

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