( is the pathogen of human tuberculosis (TB). Resistance to numerous stresses, including oxidative stress, is determinant for intracellular survival, and understanding associated mechanisms is crucial for developing new therapeutic strategies. Rv2617c has been associated with oxidative stress response when interacting with other proteins in ; however, its functional promiscuity and underlying molecular mechanisms remain elusive.
View Article and Find Full Text PDFEthambutol (EMB) is used in combination with isoniazid and rifampicin for the treatment of tuberculosis caused by . However, the incidence of EMB resistance is alarming. The EMB targets the cell wall arabinan biosynthesis.
View Article and Find Full Text PDFTuberculosis is probably the most seasoned illness of the humanity. Intricacies or subsequent death emerging from these infections are frequently connected with cytokine storm. Interleukin-6 (IL-6) plays a crucial role in the immune response to tuberculosis.
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