Near-infrared germanium PIN-photodiodes with >1A/W responsivity.

Even though efficient near-infrared (NIR) detection is critical for numerous applications, state-of-the-art NIR detectors either suffer from limited capability of detecting incoming photons, i.e., have poor spectral responsivity, or are made of expensive group III-V non-CMOS compatible materials.

Factors Associated with Information Needs and Information-Seeking Intention Among People with Cancer Experience in Hong Kong.

Information is crucial for person-centered cancer care. This study investigated sociodemographic, psychological, and communicative factors associated with perceived information needs and the intention to continue seeking information among individuals with cancer experience in Hong Kong. Data were drawn from the INSIGHTS-Hong Kong (International Studies to Investigate Global Health Information Trends) survey, which included 510 respondents with personal cancer experience or as family members and close friends of those diagnosed with cancer.

Transcriptomic Profiling Reveals Differences in Slow-Twitch and Fast-Twitch Muscles of a Cigarette Smoke-Exposed Rat Model.

Background: Cigarette smoking is known to affect muscle function and exercise capacity, including muscle fatigue resistance. Most studies showed diminished cross-sectional area and fibre type shifting in slow-twitch muscles such as the soleus, while effects on fast-twitch muscles were seldom reported and the differential responses between muscle types in response to exposure to cigarette smoke (CS) were largely unknown. This study aimed to elucidate the histomorphological, biochemical and transcriptomic changes induced by CS on both slow-twitch and fast-twitch muscles.

Dietary Pattern, Sputum DNA Methylation, and Lung Health: An Epidemiological Study in People Who Ever Smoked.

Background: We previously identified a panel of sputum DNA methylation that predicts lung aging and risk for lung cancer.

Research Question: Can the sputum methylation panel be used as a readout to derive a dietary pattern beneficial for lung health? Is this dietary pattern associated with various subjective and objective lung health phenotypes? Does this relationship vary among people who currently smoke (current smokers) vs previously smoked (former smokers)?

Study Design And Methods: Using the Lovelace Smoker Cohort (LSC), we employed the LASSO (least absolute shrinkage and selection operator) regularized Poisson regression to define a dietary pattern for sputum. Associations of the dietary pattern with objective and subjective lung health measurements were examined using generalized linear and Cox models in the LSC and the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening trial.

Assessing the spatial scale of synchrony in forest tree population dynamics.

Populations of forest trees exhibit large temporal fluctuations, but little is known about the synchrony of these fluctuations across space, including their sign, magnitude, causes and characteristic scales. These have important implications for metapopulation persistence and theoretical community ecology. Using data from permanent forest plots spanning local, regional and global spatial scales, we measured spatial synchrony in tree population growth rates over sub-decadal and decadal timescales and explored the relationship of synchrony to geographical distance.

Mindful Eating and Diet Quality Among US Adults With Lower Incomes.

Background: Mindful eating, a practice that encourages attention to sensations and awareness during the eating experience, has shown effectiveness in inducing positive behavioral changes. Mindful eating practices have been examined in relation to energy intake (i.e.

Cellular ATP demand creates metabolically distinct subpopulations of mitochondria.

Mitochondria serve a crucial role in cell growth and proliferation by supporting both ATP synthesis and the production of macromolecular precursors. Whereas oxidative phosphorylation (OXPHOS) depends mainly on the oxidation of intermediates from the tricarboxylic acid cycle, the mitochondrial production of proline and ornithine relies on reductive synthesis. How these competing metabolic pathways take place in the same organelle is not clear.

Effect of the Radical Remission Multimodal Intervention on Quality of Life of People with Cancer.

The Radical Remission Multimodal Intervention (RRMI) was developed by Kelly A. Turner, PhD, after analyzing more than 1500 cases of cancer survivors experiencing radical remission (a.k.

Ultraprocessed food intake and body mass index change among youths: a prospective cohort study.

Background: Suboptimal diets may promote undesired weight gain in youths, with high ultraprocessed food (UPF) intake becoming a significant concern in the United States.

Objectives: We evaluated the association between UPF intake and body mass index [BMI (in kg/m)] change in large United States youth cohorts.

Methods: Participants included children and adolescents (7-17 y) from the Growing Up Today Study (GUTS1 and GUTS2) who completed baseline and ≥1 follow-up diet and anthropometrics assessment (GUTS1 1996-2001: N = 15,797; GUTS2 2004-2011: N = 9720).

Development and characterization of reverse genetics systems of feline infectious peritonitis virus for antiviral research.

Feline infectious peritonitis (FIP) is a lethal, immune-mediated disease in cats caused by feline infectious peritonitis virus (FIPV), a biotype of feline coronavirus (FCoV). In contrast to feline enteric coronavirus (FECV), which exclusively infects enterocytes and causes diarrhea, FIPV specifically targets macrophages, resulting in the development of FIP. The transmission and infection mechanisms of this complex, invariably fatal disease remain unclear, with no effective vaccines or approved drugs for its prevention or control.

How can we reduce neonatal sepsis after universal group B streptococcus screening?

Background: Group B Streptococcus (GBS) infection remains a leading cause of newborn morbidity and mortality. The study aimed to determine the adherence rate to the universal screening policy a decade after its introduction. Secondly, whether the timing of antibiotics given in GBS carriers reduces the incidence of neonatal sepsis.

Photoactivable malachite green-based alkynylplatinum(II) 2,6-bis(-alkylbenzimidazol-2-yl)pyridine complexes.

Photo-responsive malachite green moieties have been incorporated into an alkynylplatinum(II) bzimpy system. The photo-caged complexes in acetonitrile solutions exhibit self-assembly properties modulable by photo-removal of the cyano protecting group. Distinct aggregate morphologies, which are facilitated by the non-covalent metal-metal and π-π stacking interactions, have been observed before and after photo-irradiation.

Pseudotumour: an uncommon complication of severe haemophilia.

Pseudotumours are uncommon complications of haemophilia, occurring in 1%-2% of patients with haemophilia. It is a slowly expanding haematoma as a result of recurrent haemorrhage, surrounded by a fibrous capsule. It can occur in both bone and soft tissue, and progressive enlargement may result in bone destruction and/or muscle and skin necrosis.

Recurrent Ileocolic Intussusception With the Appendix as the Pathologic Lead Point in Children: A Report of Two Cases and Review of Literature.

Ileocolic intussusception is a consideration in young pediatric patients with acute abdominal pain. Meckel's diverticulum is the most common pathologic lead point for intussusception in children and the appendix acting as the lead point is rare. In addition, management guidelines for recurrent ileocolic intussusception (RICI) are lacking.

Total magnesium intake and risk of frailty in older women.

Background: An adequate magnesium intake might lower the risk of frailty through its role in muscle function.

Methods: We analysed data from 81 524 women aged ≥60 years participating in the Nurses' Health Study. Total magnesium intake was obtained from repeated food frequency questionnaires administered between 1984 and 2010 and self-reported information on supplementation.

Emergency department triage decision-making by registered nurses: An instrument development study.

Aim: To develop and psychometrically test the triage decision-making instrument, a tool to measure Emergency Department Registered Nurses decision-making.

Design: Five phases: (1) defining the concept, (2) item generation, (3) face validity, (4) content validity and (5) pilot testing.

Methods: Concept definition informed by a grounded theory study from which four domains emerged.

Ultraprocessed foods, unprocessed or minimally processed foods, and risk of frailty in a cohort of United States females.

Background: Ultraprocessed foods (UPFs) and poor diet quality have been associated with frailty but existing studies had relatively short follow-up time. It is also unclear whether the association of UPF was primarily due to its correlation with poorer diet quality.

Objectives: We examined the association between unprocessed or minimally processed foods (UMFs) and UPF and risk of frailty and explored whether the association with UPF was mainly driven by poor diet quality.

Dietary inflammatory pattern and risk of hip fracture in the Nurses' Health Study.

Unlabelled: Our immune system activity is impacted by what we eat and can influence fracture risk under certain conditions. In this article, we show that postmenopausal women with a pro-inflammatory dietary pattern have an increased risk of hip fracture.

Purpose: The immune system influences bone homeostasis and can increase the risk of fracture under certain pro-inflammatory conditions.