Publications by authors named "Funan Wang"
Diagnostic accuracy and image quality evaluation of ultrashort echo time MRI in the lungs.
Medicine (Baltimore)
November 2024
This study evaluates the diagnostic accuracy of ultrashort echo time (UTE)-MRI for detecting pulmonary nodules and image quality. A total of 46 patients at our hospital underwent unenhanced computed tomography (CT) and UTE-MRI. The image quality and number of nodules detected using CT were used as the gold standards.
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- The study investigates the relationship between a chest X-ray pulmonary edema score and the timing of extubation in patients after cardiac valve surgery.
- It involved analyzing clinical data from patients in an ICU at Zhongshan Hospital, categorizing them into early (<24 hours) and delayed (≥24 hours) extubation groups.
- Results showed significant differences in various health metrics between the groups, with a positive correlation found between mechanical ventilation duration and the RALE score, suggesting the score may predict delayed extubation outcomes.
Background: In recent years, spectral CT-derived liver fat quantification method named multi-material decomposition (MMD) is playing an increasingly important role as an imaging biomarker of hepatic steatosis. However, there are various measurement ways with various results among different researches, and the impact of measurement methods on the research results is unknown. The aim of this study is to evaluate the reproducibility of liver fat volume fraction (FVF) using MMD algorithm in nonalcoholic fatty liver disease (NAFLD) patients when taking blood vessel, location, and iodine contrast into account during measurement.
View Article and Find Full Text PDFBackground: Radiation-free lung cancer screening will reduce/eliminate radiation exposure in the diagnosis and follow-up of patients with lung cancer.
Methods: This was a prospective study. The participants were recruited using convenience sampling.
Article Synopsis
- The study investigates T2 mapping as a contrast-free MRI technique for evaluating uterine tumors, comparing its effectiveness at 1.5 T and 3.0 T MRI systems.
- A total of 176 participants, including healthy subjects and those with suspected lesions, underwent MRI scans, and T2 values were calculated to assess differences in normal and abnormal uterine tissues between the two magnetic strengths.
- Results showed that 3.0 T MRI yielded significantly lower T2 values for both normal structures and lesions, with T2 values distinguishing between benign and malignant tumors effectively at both magnetic field strengths.
Article Synopsis
- The study investigates whether spectral CT imaging can differentiate between solitary lung cancer and inflammatory lesions, addressing a common diagnostic challenge.
- It involved 78 patients who underwent enhanced CT scans using Gemstone Spectral Imaging to analyze various imaging parameters related to lesion size.
- Results indicated that there were significant differences in specific imaging parameters between cancer and inflammatory groups, particularly in the smaller lesions, and correlations were noted for cancer lesions but not for inflammatory ones.
The location of an acute ischemic stroke is associated with its prognosis. The widely used Gaussian model-based parameter, apparent diffusion coefficient (ADC), cannot reveal microstructural changes in different locations or the degree of infarction. This prospective observational study was reviewed and approved by the Institutional Review Board of Xiamen Second Hospital, China (approval No.
View Article and Find Full Text PDFRational use of antibiotic is the key approach to improve the antibiotic performance and tackling of the antimicrobial resistance. The efficacy of antimicrobials are influenced by many factors: (1) bacterial status (susceptibility and resistance, tolerance, persistence, biofilm) and inoculum size; (2) antimicrobial concentrations [mutant selection window (MSW) and sub-inhibitory concentration]; (3) host factors (serum effect and impact on gut micro-biota). Additional understandings regarding the linkage between antimicrobial usages, bacterial status and host response offers us new insights and encourage the struggle for the designing of antimicrobial treatment regimens that reaching better clinical outcome and minimizing the emergence of resistance at the same time.
View Article and Find Full Text PDFObjective: To investigate the chemical constituents of Hypericum petiolulatum.
Method: The chemical constituents were isolated and purified by column chromatography on silica gel, macroporous adsorbent resin, Sephadex LH-20, and preparative HPLC. Structures of the compounds were identified by NMR and MS spectroscopic methods.