Publications by authors named "Fumiya Matsumoto"
Article Synopsis
- A chemical proteomics study using TIM-063-Kinobeads identified primary targets like CaMKKα/1 and β/2, and also highlighted potential off-target kinases such as AAK1.
- The study found a new, more potent AAK1 inhibitor, TIM-098a, which has a significantly lower IC value of 0.24 µM and selectively inhibits AAK1 without affecting CaMKK isoforms.
- TIM-098a was shown to inhibit AAK1 activity in living cells and blocked the reduction of early endosomes in HeLa cells, suggesting its potential as a selective and therapeutically valuable AAK1 inhibitor.
Case 1: An 18-year-old man. On initial examination, he was diagnosed with central retinal vein occlusion (CRVO) due to optic papillitis. He had no previous systemic and ocular medical history.
View Article and Find Full Text PDFAn ultrasonic lateral displacement sensor utilizing air-coupled ultrasound transducers is proposed. The normally-distributed far field of an ultrasound transducer in a lateral direction is taken advantage of for measuring lateral displacement. The measurement system is composed of several air-coupled ultrasound transducers as a receiver and several transmitters.
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