Publications by authors named "Fumio Kitaoka"

Article Synopsis
  • A 56-year-old man had a serious liver disease called hepatocellular carcinoma and liver cirrhosis, so he had a special treatment called transcatheter arterial embolization (TAE).
  • After five months, the cancer came back in his liver and also spread to a gland above his kidney called the left adrenal gland.
  • He had another TAE for the liver and then a different surgery called hand-assisted laparoscopic surgery (HALS) for the left adrenal gland, which helped control the cancer. This is the first time anyone has reported doing this type of surgery for cancer spreading from the liver.
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Background/aims: We report a case of solitary Peutz-Jeghers-type hamartomatous polyp of the duodenum in a 22-year-old Japanese woman along with the results of genomic analysis.

Methods/results: The patient was almost asymptomatic, though endoscopic examination revealed a solitary lobular polypoid lesion measuring 3 cm in diameter in the first portion of the duodenum. The lesion was resected endoscopically.

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Background: The present study was planned to investigate cumulative genetic changes during development and progression of gallbladder carcinoma (GBC) in clinical patients.

Materials And Methods: We examined GBC DNA from resected tissue isolated from 56 cases of GBC for loss of heterozygosity (LOH) at six loci on five chromosomal arms (1p36, 9p21, 13q14, 16q24, 17p13), using highly polymorphic microsatellite markers.

Results: High incidences of LOH at 1p36 (19/36: 53%), 9p21 (12/32: 38%), 13q14 (20/36: 56%), 16q24 (31/54: 61%), and 17p13 (15/36: 42%) were detected.

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