Publications by authors named "Fumie Hirose"
Taste disorders are common adverse effects of cancer chemotherapy that can reduce quality of life and impair nutritional status. However, the molecular mechanisms underlying chemotherapy-induced taste disorders remain largely unknown. Furthermore, there are no effective preventive measures for chemotherapy-induced taste disorders.
View Article and Find Full Text PDFTaste information is detected by taste cells and then transmitted to the brain through the taste nerve fibers. According to our previous data, there may be specific coding of taste quality between taste cells and nerve fibers. However, the molecular mechanisms underlying this coding specificity remain unclear.
View Article and Find Full Text PDFArticle Synopsis
- The renin-angiotensin system (RAS) is crucial for regulating body fluid and sodium balance, with angiotensin II (AngII) as a key component affecting taste responses.
- Previous findings showed that AngII reduces salt taste sensitivity while increasing the response to sweet tastes through its interaction with receptors in taste cells.
- In this study, researchers discovered that components of the RAS are present in mouse taste tissues and that levels of renin increase in taste cells when mice are dehydrated, suggesting a local RAS that may influence taste perception and contribute to sodium and calorie balance.