Tubular anomalous bones found in both thighs of a long-tailed macaque (Macaca fascicularis).

Tubular anomalous bones were found in both thighs of a 6-year-old male long-tailed macaque (Macaca fascicularis) bred in captivity. The bones had jagged ends and protruded from the skin. Radiographs showed that they developed in the femurs at the middle and elongated.

Breeding of African green monkeys (Cercopithecus aethiops) under indoor individually-caged conditions.

This paper reports the results of reproduction with 45 wild African green monkeys (Cercopithecus aethiops) (36 females and 9 males) during the nine years from 1981 to 1989 under indoor individually-caged conditions. In 206 cases of menstruation observed, menstrual discharge lasted for 2.5 +/- 1.

Chronological and spatial analysis of the 1996 Ebola Reston virus outbreak in a monkey breeding facility in the Philippines.

To describe the transmission pattern of natural infection with Ebola Reston (EBO-R) virus in a breeding colony, the chronological and spatial analysis of mortality during the 1996 EBO-R virus outbreak was done in this study. The EBO-R virus infection among monkeys in the facility was widespread. Over a period of 3 months, 14 out of 21 occupied units were contaminated with antigen positive animals.

Early embryonal culture of the cynomolgus monkey (Macaca fascicularis).

Ovaries of ten female cynologus monkeys (Macaca fascicularis) were superstimulated with pregnant mare serum gonadotropin (PMSG) and human chorionic gonadotropin (hCG). During this treatment, follicular development was monitored by ultrasonography. After three to four injections of PMSG, ovaries began to show an increase in their size.

Serum chorionic gonadotropin levels determined by radioreceptorassay and early diagnosis of pregnancy in the cynomolgus monkey (Macaca fascicularis).

The radioreceptorassay developed to determine serum luteinizing hormone level in the cynomolgus monkey was evaluated for its usefulness in early pregnancy diagnosis by the detection of serum chorionic gonadotropin (CG). Blood samples were collected at weekly intervals from the 1st to the 5th week after conception to determine changes in circulating levels of CG. In the pregnancy cases, serum CG levels increased to above 50 μg/ml in almost all animals.

Luteinizing hormone receptors in ovaries of the cynomolgus monkey (Macaca fascicularis) during the menstrual cycle.

Ovarian luteinizing hormone (LH) receptors were characterized using ovarian tissues from 17 cynomolgus monkeys at different phases of the menstrual cycle. Low binding affinity receptors for I-LH were observed throughout the menstrual cycle. The binding affinity of these receptors for LH (< 12 × 10 M) was approximately the same as that of ovarian LH receptors previously reported in human and nonhuman primates.

Adoption success under single-cage conditions by cynomolgus macaque mothers (Macaca fascicularis).

Retrospective data were studied to determine the success of experimental adoption by 122 cynomolgus macaques kept in individual cages at the Tsukuba Primate Center. The four types of adoption procedures included (1) singletons adopted after weaning (SAW)-21 cases; (2) singletons adopted after stillbirth (SAS)-20 cases; (3) singletons adopted after forced separation of the biological infant during the nursing period (SAF)-4 cases; and (4) adoption of a second "twin" while still nursing a biological infant (TA)-77 cases. Adoption was defined as successful if the mother nursed the foster infants for at least 7 days.

The inheritance mode of simian-type E, F, and GH blood groups in cynomolgus monkeys.

The mode of inheritance of four different red cell antigens (E, F, G, and H), detected by alloimmune reagents prepared by us for the cynomolgus monkey, was studied. The results of the segregation analysis suggest that each antigen is inherited in an autosomal dominant manner. Both the random sample analysis and family study revealed that two of these red cell antigens (E and F) probably represent the products of two independent genes while the expression of the other two antigens (G and H is governed by two autosomal codominant alleles.