Type V phosphodiesterase inhibitor treatments for erectile dysfunction increase testosterone levels.

Objective: Lack of sexual activity due to erectile dysfunction (ED) decreases testosterone (T) levels through a central effect on the hypothalamic-pituitary axis. In this paper we studied the effect of different type V phosphodiesterase (PDE5) inhibitor treatments for ED on the reversibility of this endocrine pattern.

Design: Open-label, retrospective study.