Effect of Lower Extremity Nerve Decompression in Patients With Painful Diabetic Peripheral Neuropathy: The Diabetic Neuropathy Nerve Decompression Randomized, Observation Group and Placebo Surgery-Controlled Clinical Trial.

Objective: To evaluate the effect of nerve decompression on pain in patients with lower extremity painful diabetic peripheral neuropathy (DPN).

Background: Currently, no treatment provides lasting relief for patients with DPN. The benefits of nerve decompression remain inconclusive.

Study protocol paper for the multi-site feasibility evaluation of mobile and technology-assisted aftercare services for crisis stabilization units.

Background: Law enforcement frequently responds to substance abuse and mental health crises. Crisis stabilization units (CSUs) operate as a public-receiving facility to provide short-term stabilization services for individuals experiencing these crises and offer law enforcement an important alternative to arrest. However, there is limited understanding about how and when law enforcement decides to use CSUs.

Ehrlichiosis-Associated Hemophagocytic Lymphohistiocytosis: A Case Series and Review of the Literature.

Background: Human monocytic ehrlichiosis (HME) is a potentially life-threatening tick-borne illness. HME-associated hemophagocytic lymphohistiocytosis (HLH) is a rare entity with a paucity of published literature regarding treatment and outcome. We present the clinical features, treatment, and outcomes of 4 patients at our institutions with HME-associated HLH.

Heat Transfer Enhancement in the Microscale: Optimization of Fluid Flow.

The focus of this paper is to investigate the effects of the addition of a connector between two serial microchannels. The idea of adding connector at the inlet of microchannels to enhance the random motion of molecules or nanoparticles in low Reynolds numbers was developed in our research group for the first time. It was experimentally determined that the shape of a connector between two microchannels has a significant impact on the enhancement of the random motion of molecules or nanoparticles.

Hybrid Nanofluid Thermal Conductivity and Optimization: Original Approach and Background.

The focus of this paper was to develop a comprehensive nanofluid thermal conductivity model that can be applied to nanofluids with any number of distinct nanoparticles for a given base fluid, concentration, temperature, particle material, and particle diameter. For the first time, this model permits a direct analytical comparison between nanofluids with a different number of distinct nanoparticles. It was observed that the model's average error was ~5.

Nanofluid Heat Transfer: Enhancement of the Heat Transfer Coefficient inside Microchannels.

The purpose of this paper is to investigate the effects of a connector between two microchannels, for the first time. A brief literature review is provided to offer a better understanding on the impacts of concentration and the characteristics of nanoparticles on thermal conductivity, viscosity, and, consequently, the heat transfer coefficient inside the microchannels. The given literature review aims to help engineer nanofluids to enhance the heat transfer coefficient inside the microchannels.

Thermal Conductivity and Viscosity: Review and Optimization of Effects of Nanoparticles.

This review was focused on expressing the effects of base liquid, temperature, possible surfactant, concentration and characteristics of nanoparticles including size, shape and material on thermal conductivity and viscosity of nanofluids. An increase in nanoparticle concentration can lead to an increase in thermal conductivity and viscosity and an increase in nanoparticle size, can increase or decrease thermal conductivity, while an increase in nanoparticle size decreases the viscosity of the nanofluid. The addition of surfactants at low concentrations can increase thermal conductivity, but at high concentrations, surfactants help to reduce thermal conductivity of the nanofluid.

Ethical Artificial Intelligence for Digital Health Organizations.

This technical report describes the methods undertaken by a US-based Digital Health company (X2AI or X2 for short) to develop an ethical code for startup environments and other organizations delivering emotional artificial intelligence (AI) services, especially for mental health support. With a growing demand worldwide for scalable, affordable, and accessible health care solutions, the use of AI offers tremendous potential to improve emotional well-being. To realize this potential, it is imperative that AI service providers prioritize clear and consistent ethical guidelines that align with global considerations regarding user safety and privacy.

Using Psychological Artificial Intelligence (Tess) to Relieve Symptoms of Depression and Anxiety: Randomized Controlled Trial.

Background: Students in need of mental health care face many barriers including cost, location, availability, and stigma. Studies show that computer-assisted therapy and 1 conversational chatbot delivering cognitive behavioral therapy (CBT) offer a less-intensive and more cost-effective alternative for treating depression and anxiety. Although CBT is one of the most effective treatment methods, applying an integrative approach has been linked to equally effective posttreatment improvement.

REBEL WITHOUT A CAUSE: A PSYCHOANALYTIC AND FAMILY-LIFE-CYCLE VIEW OF EMERGING ADULTHOOD IN THE FILM.

The period during which grown children leave home and establish a new, self-supporting family is called emerging adulthood. This paper uses psychoanalytic concepts and family-life-cycle theory to analyze the film Rebel without a Cause () as a dramatic example of three families going through this phase. Freud's () rescue-motif of the child trying to save an endangered peer to repay his parents for having been nurtured is also characteristic of this period and is considered practice for parenting the next generation.

Predictors of postoperative pain trajectories in adolescent idiopathic scoliosis.

Study Design: Prospective observational study.

Objective: To determine the typical trajectory of pain during the first 6 months after spinal fusion surgery for adolescent idiopathic scoliosis (AIS) and the extent to which certain demographic, medical, and psychological variables modify this trajectory.

Summary Of Background Data: Pain after spinal fusion surgery for AIS may not improve predictably with elapsed healing time, and limited data exist on predictors of the course of pain during the initial months after surgery.

'Don't save her'- Sigmund Freud meets Project Pat: the rescue motif in hip-hop.

Freud originally explicated the dynamics of rescue wishes by describing men who fell in love with prostitutes. He saw this attempt at attachment as driven by the man's wish to repay his parents for giving him life. Many subsequent writers shift this emphasis, seeing rescue wishes as motivated by aggressive oedipal competition with the father.

Pharmacokinetic properties of esomeprazole in children aged 1 to 11 years with symptoms of gastroesophageal reflux disease: a randomized, open-label study.

Objective: The aim of this study was to assess the overall exposure, other pharmacokinetic (PK) properties, and tolerability of esomeprazole magnesium after repeated oral doses of 5, 10, and 20 mg in pediatric patients who had symptoms of gastroesophageal reflux disease (GERD).

Methods: This randomized, open-label study was conducted at West Coast Clinical Trials, Long Beach, California. Boys and girls aged 1 to 11 years who had a clinical diagnosis of GERD were included and stratified by age (1-5 years [younger group] and 6-11 years [older group]).

Pharmacokinetic properties of esomeprazole in adolescent patients aged 12 to 17 years with symptoms of gastroesophageal reflux disease: A randomized, open-label study.

Objective: The aim of this study was to assess the pharmacokinetic (PK) properties and tolerability of esomeprazole 20 and 40 mg after single and repeated oral doses in adolescents with symptoms of gastroesophageal reflux disease (GERD).

Results: The study included 15 boys and 13 girls (mean age, 14.3 years).

Developing your leadership pipeline.

Why do so many newly minted leaders fail so spectacularly? Part of the problem is that in many companies, succession planning is little more than creating a list of high-potential employees and the slots they might fill. It's a mechanical process that's too narrow and hidebound to uncover and correct skill gaps that can derail promising young executives. And it's completely divorced from organizational efforts to transform managers into leaders.

A crossover comparison of bromfenac sodium, naproxen sodium, and placebo for relief of pain from primary dysmenorrhea.

Single and multiple oral doses of bromfenac sodium (10 or 50 mg) were compared with naproxen sodium (550 mg loading/275 mg repeat doses) for the relief of pain from primary dysmenorrhea in 54 women using a crossover design. Pain intensity and pain relief were assessed over 6 h after the first dose, and global ratings were made at the end of day 1 and on day 2. A single dose of bromfenac 10 or 50 mg was as effective as the loading dose of naproxen sodium (550 mg) in relieving the pain from dysmenorrhea through a 6-h period.

Metastatic squamous cell carcinoma of the tonsil presenting as multiple cystic neck masses. Report of a case with fine needle aspiration findings.

A case of squamous cell carcinoma with multiple cystic metastases to the neck is reported. The tumor originally presented as a tender left neck mass clinically misdiagnosed as an abscess secondary to infected dental caries. Subsequently, multiple cervical neck cysts developed, and fine needle aspiration (FNA) of two of them demonstrated metastatic squamous cell carcinoma.

The documentation dilemma: an integrated solution.

Every home healthcare manager must contend with the demands of documentation. One approach to ensure quality and address staff concerns is presented.

Autologous fibrin tissue adhesive for ossicular reconstruction in cats.

Autologous fibrin tissue adhesive is currently the most promising adhesive for otologic use with respect to strength and biocompatibility without the risk of transmissable disease that is of concern with the commercially prepared fibrin adhesive. We set out to evaluate the practicality of preparing autologous fibrin adhesive in cats and to see if the adhesive's duration and strength of bonding was sufficient to allow natural tissue union to occur with various grafting materials. Autologous fibrin adhesive was prepared preoperatively from ten cats using the ammonium sulfate precipitation technique.

Effects of three methods of restraint an in rhesus and african green monkeys intravenous glucose tolerance testing.

The intravenous administration of 0.75 gm glucose per kg and the measurement of serum glucose pretest and at 10, 20, 30, 60, 90 and 120 minutes constitute a satisfactory protocol for intravenous glucose tolerance testing of Rhesus (Macaca mulatto) and African Green (Cercopithecus aethiops) monkeys. No significant differences were noted between animals restrained with ketamine hydrochloride and those restrained with sodium pentobarbital, but the African Green males and females and the male Rhesus monkeys yielded significantly different results while being manually restrained.

A study of professed reasons for beginning and continuing heroin use.

Eighty male ex-heroin addicts were given a standardized interview to investigate Their reasons for beginning and continuing heroin use. The relative popularity of motives is presented. Changes in popularity of motives at different stages of addiction were found, and a view of the motivational development of addiction is discussed.