The optimisation and application of an analytical method based on gas chromatography coupled to quadrupole time-of-flight mass spectrometry (GC-QToF-MS) is proposed for the first time for the characterisation and identification of mastic ( sp.) resin in archaeological samples. The GC-QToF-MS method demonstrated higher sensitivity compared to single quadrupole GC-MS and enabled enhanced structural elucidation power to be exploited, particularly due to the high mass resolution and accuracy, the possibility to use standard and low ionisation energies as well as its tandem MS capabilities.
View Article and Find Full Text PDFSamples taken from the canopic jars of Djehutyhotep, chief of Tehkhet (Debeira), Lower Nubia, and local versions of Egyptian canopic jars from Sai, Upper Nubia, suggest that the materials used for mortuary ritual unguents in Nubia may have differed from those used in Egypt. Nubian samples consisted of plant gum and bitumen, whereas those from Egypt conformed to the standardizing black resinous liquid recipe used for mummification and other funerary rituals. However, there may be time frame issues to be considered as most samples analyzed from Egypt date to later periods.
View Article and Find Full Text PDFDevelopmental and lifespan examinations of methamphetamine use among gay, bisexual, and other men who have sex with men (GBM) remain limited. We used a feminist trauma framework to examine potential links between childhood trauma, trauma-related stressors, and methamphetamine use among GBM. From June 2018 to October 2018, semi-structured interviews ( = 33) were conducted with GBM across British Columbia.
View Article and Find Full Text PDFCrystal methamphetamine (CM) disproportionately impacts gay, bisexual, and other men who have sex with men (gbMSM). However, not all gbMSM are interested in changing their substance use. The present study aimed to examine whether participant-preferred service characteristics were associated with their readiness to change.
View Article and Find Full Text PDFBackground: This study examined the perceived difficulty of getting help with substance use among sexual and gender minorities who have sex with men (SGMSM) who use methamphetamine during the early COVID-19 period.
Methods: SGMSM, aged 18+, who reported sex with a man and methamphetamine use in the past 6 months were recruited to complete an online survey using online advertisements. Ordinal regression models examined predictors of greater perceived difficulty of getting help.
Unlabelled: Improving the discharge process is an area of focus throughout healthcare organizations. Capacity constraints, efficiency improvement, patient safety, and quality care are driving forces for many discharge process workgroups.
Methods: Following the Pareto principle, we focused on improving the discharge process on the medical-surgical units that received the most patients admitted from the emergency department.
Black organic coatings and ritual deposits on ancient Egyptian coffins and cartonnage cases are important and understudied sources of evidence about the rituals of funerary practice. Sometimes, the coatings were applied extensively over the surface of the coffin, resembling paint; in other cases, they were poured over the mummy case or wrapped body, presumably as part of a funerary ritual. For this study, multiple samples of black coatings and ritual liquids were taken from 20 Egyptian funerary items dating to a specific time period (c.
View Article and Find Full Text PDFBitumen has been identified for the first time in Egyptian occupied Nubia, from within the town of Amara West, occupied from around 1300 to 1050 BC. The bitumen can be sourced to the Dead Sea using biomarkers, evidencing a trade in this material from the eastern Mediterranean to Nubia in the New Kingdom or its immediate aftermath. Two different end uses for bitumen were determined at the site.
View Article and Find Full Text PDFBackground: The emergence of biomedical and seroadaptive HIV prevention strategies has coincided with a decline in condom use among gay men.
Methods: We undertook a social ecological analysis of condom use and perceptions using nineteen semi-structured interviews with HIV negative gay men in Vancouver, Canada who used HAART-based prevention strategies.
Results: Contributors to inconsistent condom use were found at various levels of the social ecological model.
From a health perspective, group sex parties represent risk environments, as multiple sexual partners and polysubstance use associated with these parties may present risk practices for sexually transmitted infection (STI) transmission. At the same time, group sex parties exemplify sex as recreation, expressed in contemporary sociological theory as sex as leisure or play. In this paper, we report on the findings of an exploratory qualitative study conducted with group sex party attendees and hosts/organisers in a mid-sized Canadian city.
View Article and Find Full Text PDFMany older adults age at home, cared for by family caregivers. Nurse educators need effective educational strategies to teach students family caregiving issues. This article examines how the Life of a Caregiver (LOC) simulation influences students' understanding and knowledge of aging, family caregiving issues, and related community services.
View Article and Find Full Text PDFThe dose-response analyses of cancer and noncancer health effects of aldrin and dieldrin were evaluated using current methodology, including benchmark dose analysis and the current U.S. Environmental Protection Agency (U.
View Article and Find Full Text PDFPurpose: The objective of the present study was to investigate whether speakers with hypophonia, secondary to Parkinson's disease (PD), would increases their vocal intensity when speaking in a noisy environment (Lombard effect). The other objective was to examine the underlying laryngeal and respiratory strategies used to increase vocal intensity.
Methods: Thirty-three participants with PD were included for study.
Int J Environ Res Public Health
January 2014
In 2011, World Health Organization (WHO) scientists reported that a significant percentage of global deaths and disability-adjusted life years (DALYs) in 2004 could be attributed to chemicals. The 2011 review focused only on certain chemicals, however, and concluded that the global burden of disease was underestimated because of serious data gaps. While various chemical assessment documents have identified research needs for individual chemicals, a systematic review of such documents to identify research themes that could be applied to the multitude of chemicals for which there is little information has not been done.
View Article and Find Full Text PDFObjectives: We examined the relationship between radiation and excess deaths from mesothelioma among deceased nuclear workers who were part of the US Transuranium and Uranium Registries.
Methods: We performed univariate analysis with SAS Version 9.1 software.
J Air Waste Manag Assoc
December 2011
This study developed and tested a protocol for monitoring odors near a Concentrated Animal Feeding Operation (CAFO). The Nasal Ranger, a portable field olfactometry instrument, was used by a panel of trained individuals to conduct the monitoring near a swine CAFO. Monitors were selected based on olfactory sensitivity, scheduling availability, and lack of association with the CAFO or residential neighbors of the CAFO.
View Article and Find Full Text PDFMed Sci Sports Exerc
October 2002
A-kinase anchoring proteins (AKAPs) tether cyclic AMP-dependent protein kinases and thereby localize phosphorylation of target proteins and initiation of signal-transduction processes triggered by cyclic AMP. AKAPs can also be scaffolds for kinases and phosphatases and form macromolecular complexes with other proteins involved in signal transduction. Akap4 is transcribed only in the postmeiotic phase of spermatogenesis and encodes the most abundant protein in the fibrous sheath, a novel cytoskeletal structure present in the principal piece of the sperm flagellum.
View Article and Find Full Text PDFJ Neurol Neurosurg Psychiatry
September 2000
Objective: To measure strength, aerobic exercise capacity and efficiency, and functional incapacity in patients with chronic fatigue syndrome (CFS) who do not have a current psychiatric disorder.
Methods: Sixty six patients with CFS without a current psychiatric disorder, 30 healthy but sedentary controls, and 15 patients with a current major depressive disorder were recruited into the study. Exercise capacity and efficiency were assessed by monitoring peak and submaximal oxygen uptake, heart rate, blood lactate, duration of exercise, and perceived exertion during a treadmill walking test.
Objectives: Adults with GH deficiency complain frequently of low energy levels resulting in a low perceived quality of life. Body composition is altered, with increased fat mass and decreased lean body mass, and muscle strength is reduced. The aims of this study were to determine the effects of GH replacement on physical performance and body composition in GH deficient (GHD) adults.
View Article and Find Full Text PDFThis study examined the effect of sodium citrate ingestion on high-intensity cycling performance in repeated 45-sec bouts. Twelve subjects (9 male and 3 female) ingested either a sodium citrate solution (0.3 g x kg-1 body mass[BM]) or a placebo 90 min prior to exercise.
View Article and Find Full Text PDFObjective: To test the efficacy of a graded aerobic exercise programme in the chronic fatigue syndrome.
Design: Randomised controlled trial with control treatment crossover after the first follow up examination.
Setting: Chronic fatigue clinic in a general hospital department of psychiatry.