Publications by authors named "Fulai Yuan"

In recent years, a surge in literature on psychological nurse resilience, largely driven by the COVID-19 pandemic, has prompted the need for a comprehensive understanding of the current state and emerging trends through reliable methodologies. The purpose of this study was to analyzes the research on nurses' psychological resilience through bibliometrics to understand the current situation, foundation, and hotspot of this research field. The Web of Science core collection database was used as the search source, and CiteSpace analysis software was employed to conduct bibliometric analysis on authors, countries, institutions, keywords, and references of nurse psychological resilience-related literature published from the establishment of the database to July 11, 2023.

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Background: Cumulative evidence has consistently shown that white matter (WM) disruption is associated with cognitive decline in geriatric depression. However, limited research has been conducted on the correlation between these lesions and cognitive performance in untreated young adults with major depressive disorder (MDD), particularly with the specific segmental alterations of the fibers.

Method: Diffusion tensor images were performed on 60 first-episode, treatment-naïve young adult patients with MDD and 54 matched healthy controls (HCs).

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Background: Insomnia disorder (ID) is one of the most common mental disorders. Research on ID focuses on exploring its mechanism of disease, novel treatments and treatment outcome prediction. An emerging technique in this field is the use of electroencephalography (EEG) microstates, which offer a new method of EEG feature extraction that incorporates information from both temporal and spatial dimensions.

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Article Synopsis
  • Betel quid (BQ) is a widely used psychoactive agent with around 600 million users, and those with dependence disorder display deficits in executive function.
  • The study employed resting-state functional MRI to compare 55 BQ-dependent individuals with 54 healthy controls, revealing significant differences in the connectivity and functionality of the executive control network (ECN).
  • Findings indicated impaired executive function and weaker functional connectivity in BQD patients, suggesting potential targets for future intervention strategies.
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Oxidative stress is essential in brain injury after intracerebral hemorrhage (ICH). Ferroptosis, iron-dependent oxidative cell death, overwhelms the antioxidant system. Recently, Olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) hold great potential for treating ferroptosis-mediated oxidative brain damage after ICH.

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Background: Betel quid (BQ) is the fourth most popular psychoactive agent worldwide. Neuroimaging studies have showed that substance-addicted individuals including alcohol, heroin, nicotine and other addictive substance exhibit altered activity patterns of the salience network (SN). However, no study has yet investigated the neural correlates of the resting-state SN and BQ dependence (BQD)-related physiopathological characteristics.

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Areca nut (AN) is widely consumed all over the world, bringing great harm to human health and economy. Individuals with AN chewing are at high risk of cardiovascular disease and impaired immune system and metabolic system. Despite a growing number of studies having reported on the adverse effects brought by AN chewing, the exact mechanism of it is limited and the need for additional exploration remains.

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Article Synopsis
  • A study investigated the differences in neuro-metabolite concentrations in the anterior cingulate cortex (ACC) between young adults with major depressive disorder (MDD) and healthy controls, focusing on two subregions: the pregenual ACC (pACC) and anterior midcingulate cortex (aMCC).
  • Results showed that MDD patients had higher levels of glutamate and glutamine in the pACC and higher myo-inositol in the aMCC compared to controls, indicating pronounced metabolic changes in the MDD group.
  • The findings suggest that the pACC and aMCC may have different roles in MDD, highlighting the regional metabolic differences in the ACC and contributing to
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Background: Neuronal death due to over-oxidative stress responses defines the pathology of cerebral ischemic/reperfusion (I/R) insult. Ferroptosis is a form of oxidative cell death that is induced by disruption of the balance between antioxidants and pro-oxidants in cells. However, the potential mechanisms responsible for cerebral I/R-induced ferroptotic neuronal death have not been conclusively determined.

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The novel coronavirus 2019 (COVID-19) pandemic represents one of the biggest global health threats in the last two decades, so researchers around the world are searching for solutions and treatments for COVID-19. At the time of writing, there are no specific drugs that have demonstrated suitable effectiveness in treating COVID-19. The current challenge involves designing tools for the prevention, rapid and accurate diagnosis, drug delivery, and effective treatment of this novel coronavirus.

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Restoring the normal masticatory function of broken teeth is a challenging task primarily due to the defect location and size of a patient's teeth. In recent years, although some representative image-to-image transformation methods (e.g.

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The primary objective of this study was to identify the metabolic pattern in the brains of betel quid dependent (BQD) individuals using F-2-fluoro-2-deoxy-D-glucose-positron emission tomography ( F-FDG-PET). A total of 42 individuals (16 BQD individuals and 26 healthy controls, HCs) enrolled at the Department of Nuclear Medicine of Xiangya Hospital underwent brain F-FDG-PET. Group comparisons using statistical parametric mapping (SPM) were performed to identify the F-FDG-PET patterns.

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Betel quid is the fourth most popular psychoactive agent worldwide. Imaging studies have found altered brain structure in prefrontal cortex (PFC) in betel-quid dependent (BQD) chewers. However, the brain function in PFC associated with BQ use still remains unclear.

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: Betel quid dependency (BQD) is characterized by functional and structural brain alterations. Trait impulsivity may influence substance dependence by impacting its neurobiological underpinnings in the frontostriatal circuit. However, little is known about the trait impulsivity and its neural correlates in individuals with BQD.

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Previous studies have suggested that resting-state functional connectivity plays a central role in the physiopathology of major depressive disorder (MDD). However, the individualized diagnosis of MDD based on resting-state functional connectivity is still unclear, especially in first episode drug-naive patients with MDD. Resting state functional magnetic resonance imaging was enrolled from 30 first episode drug-naive patients with MDD and age- and gender-matched 31 healthy controls.

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The tooth defect is a frequently occurring disease within the field of dental clinic. However, the traditional manual restoration for the defective tooth needs an especially long treatment time, and dental computer aided design and manufacture (CAD/CAM) systems fail to restore the personalized anatomical features of natural teeth. Aiming to address the shortcomings of existed methods, this article proposes an intelligent network model for designing tooth crown surface based on conditional generative adversarial networks.

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The tooth preparation margin line has a significant impact on the marginal fitness for dental restoration. Among the previous methods, the extraction of margin line mainly relies on manual interaction, which is complicated and inefficient. Therefore, we propose a method to extract the margin line with the convolutional neural network based on sparse octree (S-Octree) structure.

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Background: Betel quid is the fourth most popular psychoactive agent worldwide. Neuroimaging studies have suggested betel-quid dependence is accompanied by abnormality in brain structure and function. However, the neural correlates of executive function deficit and prefrontal cortical thickness associated with betel-quid chewing still remain unclear.

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The conventional technique for the fabrication of complete dentures is complex, with a long fabrication process and difficult-to-control restoration quality. In recent years, digital complete denture design has become a research focus. Digital complete denture tooth arrangement is a challenging issue that is difficult to efficiently implement under the constraints of complex tooth arrangement rules and the patient's individualized functional aesthetics.

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The orthopedic application of Zn is limited owing to the poor strength and low plasticity. In this study, a novel strategy by combining rapid solidification obtained by selective laser melting (SLM) and alloying with Mg was proposed to improve the mechanical properties of Zn. The microstructures, mechanical properties, as well as in vitro cytocompatibility of SLM processed Zn-xMg (x = 0-4 wt%) were studied systematically.

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LncRNAs have emerged as a novel class of critical regulators of cancer. We aimed to construct a landscape of lncRNAs and their potential target genes in lung adenocarcinoma. Genome-wide expression of lncRNAs and mRNAs was determined using microarray.

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Betel quid (BQ) is a commonly consumed psychoactive substance, which has been regarded as a human carcinogen. Long-term BQ chewing may cause Diagnostic and Statistical Manual of Mental Disorders-IV dependence symptoms, which can lead to decreased cognitive functions, such as attention and inhibition control. Although betel quid dependence (BQD) individuals have been reported with altered brain structure and function, there is little evidence showing white matter microstructure alternation in BQD individuals.

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Betel quid (BQ) is one of the most commonly consumed psychoactive substances. It has been suggested to be associated with various health issues, especially oral cancer. Evidence also points to possible decreased cognitive functions after long-term BQ chewing, such as attention and inhibition control.

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The inherent brittleness of bioceramics restricts their applications in load bearing implant, although they possess good biocompatibility and bioactivity. In this study, molybdenum disulfide nanoplatelets (MSNPs) were used to reinforce bioceramics (MgSiO/CaSiO) scaffolds fabricated by selective laser sintering (SLS). The fracture mode of scaffolds was transformed from transgranular to mixed trans- and intergranular.

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Bioactivity and biocompatibility are crucial for tissue engineering scaffolds. In this study, hydroxyapatite (HAP) was incorporated into polyetheretherketone/polyglycolicacid (PEEK/PGA) hybrid to improve its biological properties, and the composite scaffolds were developed via selective laser sintering (SLS). The effects of HAP on physical and chemical properties of the composite scaffolds were investigated.

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