Publications by authors named "Fuki Hayakawa"
Article Synopsis
- * A 76-year-old man with obstructive jaundice underwent ERCP, but difficulties arose during insertion, leading to mild oral bleeding and the discovery of a tumor in the pyriform sinus via EGD.
- * The case highlights the need for caution and thorough evaluation when faced with unexpected resistance during endoscopic procedures, particularly for less experienced endoscopists.
Article Synopsis
- * Single-balloon endoscopy was performed to manage biliary drainage, revealing a scar-like feature around the anastomosis and a milky whitish area indicating inflammation and fibrosis.
- * Endoscopic dilatation through a pinhole in the stricture was successfully performed, and a plastic stent was placed, demonstrating a positive outcome and highlighting the utility of targeting the MWA as a landmark in guiding endoscopic interventions for challenging HJAS cases.
Article Synopsis
- The study aimed to investigate the effects of pemafibrate on non-alcoholic steatohepatitis (NASH) using a mouse model.
- Forty-two male C57BL/6J mice were divided into three groups: a control group, a DSS group receiving a chemical treatment to induce NASH, and a DSS + PEM group receiving pemafibrate along with the induced diet.
- Results indicated that pemafibrate reduced liver fat, inflammation, fibrosis, and tumor formation in the NASH model, suggesting its potential as a treatment option.
Article Synopsis
- Transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma can lead to complications like fever, abdominal pain, and liver dysfunction.
- In a 68-year-old male patient, persistent symptoms after TACE were linked to bile duct obstruction from necrotic tumor material.
- The case highlights the need to consider bile duct issues when evaluating post-TACE complications.
Article Synopsis
- - The study focuses on creating a stable, low-mortality animal model of nonalcoholic steatohepatitis (NASH) using a choline-deficient, high-fat diet combined with dextran sulfate sodium treatment to better understand NASH progression and related liver tumors.
- - Results showed that mice in the CDHF+DSS group experienced weight differences and exhibited signs of inflammation and liver changes as revealed by abdominal ultrasonography, indicating a successful model for studying NASH.
- - This new NASH model allows for non-invasive monitoring of liver condition through ultrasound, potentially reducing the need for euthanizing animals during research and promoting better animal welfare practices.
A 70-year-old Japanese man with a submucosal gastric mass that continued to increase in size underwent endoscopic submucosal dissection using the pocket creation method. Histologically, some epithelial cell nuclei were enlarged, but there was little atypia overall and no sign of malignancy, suggesting a diagnosis of submucosal heterotopic gastric gland (SHGG). SHGG that enlarges over time has been associated with gastric cancer, but a preoperative diagnosis is difficult.
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- A study was conducted to assess the effectiveness and safety of a duckbill-type anti-reflux self-expandable metal stent (D-ARMS) for treating distal malignant biliary obstruction associated with duodenal invasion.* -
- Ten patients were analyzed; results showed no instances of non-occlusion cholangitis, but 20% experienced recurrent biliary obstruction (RBO), primarily due to sludge and overgrowth.* -
- The D-ARMS demonstrated promise as a suitable option for this condition, with a median time to RBO of 382 days and only one adverse event reported (cholecystitis).*