Publications by authors named "Fujuan Ma"
Article Synopsis
- * Melatonin (MLT), known for its role in sleep regulation, has shown potential analgesic effects in NP, particularly through its action on the anterior cingulate cortex (ACC) and MLT receptor 2 (MTR).
- * The study found that MLT influences pain management by modulating neuronal excitability and microglial activation in the ACC, suggesting a new therapeutic approach for treating chronic NP.
Objective: Inflammatory pain, is caused by lesions or diseases of the somatosensory tissue, is a prevalent chronic condition that profoundly impacts the quality of life. However, clinical treatment for this type of pain remains limited. Traditionally, the stimulation of microglia and subsequent inflammatory reactions are considered crucial elements to promote the worsening of inflammatory pain.
View Article and Find Full Text PDFInflammatory pain is a commonly observed clinical symptom in a range of acute and chronic diseases. However, the mechanism of inflammatory pain is far from clear yet. Rab11a, a small molecule guanosine triphosphate enzyme, is reported to regulate orofacial inflammatory pain in our previous works.
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