Publications by authors named "Fujino Obata"

Article Synopsis
  • PET imaging using Zr is gaining traction for visualizing immune and cancer cells, but has limitations due to low image quality from gamma ray emissions.
  • A new prototype has been developed to improve Compton imaging within PET by redesigning the scatter detector and optimizing image reconstruction methods.
  • The upgraded WGI system showed enhanced imaging performance, including improved angular resolution, sensitivity, and reduced noise, demonstrating successful in-vivo imaging of a mouse with tumor burden after Zr labeled antibody injection.
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. Time-of-flight (TOF) is an important factor that directly affects the image quality of PET systems, and various attempts have been made to improve the coincidence resolving time (CRT) of PET detectors. For independent readout detectors, the timing is acquired for each silicon photomultiplier (SiPM), so they are less sensitive to diffused scintillation light, resulting in a better CRT.

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. A crosshair light sharing (CLS) PET detector as a TOF-DOI PET detector with high spatial resolution has been developed. To extend that work, a detector calibration method was developed to achieve both higher coincidence resolving time (CRT) and DOI resolution.

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In carbon ion therapy, the visualization of the range of incident particles in a patient body is important for treatment verification. In-beam positron emission tomography (PET) imaging is one of the methods to verify the treatment in ion therapy due to the high quality of PET images. We have shown the feasibility of in-beam PET imaging of radioactiveO andC ion beams for range verification using our OpenPET system.

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Time-of-flight (TOF) and depth-of-interaction (DOI) are well recognized as important information to improve PET image quality. Since such information types are not correlated, many TOF-DOI detectors have been developed but there are only a few reports of high-resolution detectors (e.g.

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