Publications by authors named "Fugui Lin"
Background: The role of conventional liver function clinical laboratory marker De Ritis Ratio in evaluating the prognosis, assisting diagnosis, and monitoring therapeutic efficacy of cancer is gaining increasing attention, especially in the last decade. According to the most recent articles, the De Ritis Ratio functions have progressed, which indicates that the De Ritis Ratio appears to be a promising tumor marker. The aim of this review was to evaluate the clinical importance from studies made on this subject.
View Article and Find Full Text PDFGastric cancer (GC) is associated with high morbidity and mortality rates. Thus, early diagnosis is important to improve disease prognosis. Endoscopic assessment represents the most reliable imaging method for GC diagnosis; however, it is semi-invasive and costly and heavily depends on the skills of the endoscopist, which limit its clinical applicability.
View Article and Find Full Text PDFArticle Synopsis
- - Aquaporin 1 (AQP1) is a protein found in endothelial cells that helps manage water flow and is crucial for various bodily functions.
- - The study investigated how the Mef2c protein regulates AQP1 gene expression in endothelial cells by working together with Sp1 to enhance transcription.
- - Results showed that increasing levels of Mef2c and Sp1 led to better migration and formation of structures in endothelial cells, effects that were reversed when AQP1 was knocked down, signifying AQP1's important role in blood vessel formation.