Publications by authors named "Fuesun Okan"

: As an endocrine organ, adipose tissue produces adipokines that influence coronary artery disease (CAD). The objective of this study was to assess the potential value of CTRP5 and chemerin in differentiating coronary computed tomography angiography (CCTA)-confirmed coronary artery disease (CAD) versus non-CAD. Secondarily, within the CCTA-confirmed CAD group, the aim was to investigate the relationship between the severity and extent of CAD, as determined by coronary artery calcium score (CACS), and the levels of CTRP5 and chemerin.

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The World Health Organization (WHO) highlights the importance of improving the design of public health interventions and policies by applying principles from the behavioral sciences. These sciences play a crucial role in modifying behaviors and addressing a wide range of health challenges, from pandemics and chronic diseases to the climate crisis. This article examines the transformative impact of behavioral sciences on public health promotion, focusing on the factors that influence decision-making and intervention strategies based on the six principles developed by the WHO Technical Advisory Group.

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This study aims to develop the "Spiritual Entrepreneurship Orientation Scale" to explore how entrepreneurs incorporate spiritual values and social responsibilities into their business activities. The objective is to create a tool that accurately measures how entrepreneurs integrate spiritual values into their decisions, their understanding of purposeful entrepreneurship and their awareness of spiritual resilience and social responsibility. The study proceeded in three phases: a literature review, expert consultation and preliminary testing to ensure content validity.

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Background: Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is an important clinical entity that is rare and may develop with a Type IV delayed type hypersensitivity immune response to drug antigens. The incidence and characteristics of SDRIFE attributed to COronaVIrus Disease of 2019 (COVID-19) vaccines remain unclear, this issue requires further elucidation.

Objective: We aim to investigate the vaccine-related-SDRIFE and potential immunogens of COVID-19 vaccines through a literature review accompanied by a real case.

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Background: Digital information sources provide adolescents with quick access to health-related information. Schools are ideal for promoting digital health literacy and enabling students to handle such information safely. The aim of this paper is to present initial results from a representative study on learning digital health literacy in schools, with a focus on sociodemographic and socioeconomic differences.

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Tartrazine, an azo dye prevalent in pharmaceuticals and food items, was investigated for its impact on fetal development, specifically examining visceral and skeletal abnormalities in rat offspring exposed to daily oral doses throughout pregnancy. Fourteen pregnant rats were randomly assigned to control and tartrazine groups (seven animals each), with tartrazine administered via oral gavage at 7.5 mg/kg throughout gestation.

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Article Synopsis
  • - Sepsis is a serious condition characterized by inflammation and cell death, often leading to multiple organ failure, requiring quick medical attention; lipopolysaccharide (LPS) triggers inflammatory responses through specific receptors like TLR-2.
  • - The study explores the role of melatonin (MEL) in reducing lung injury caused by LPS-induced septic shock in rats, highlighting its potential to lower the expressions of inflammatory markers NEK7, TLR2, and NLRP3.
  • - Results showed that melatonin treatment reduced lung tissue damage, cell infiltration, and wall thickening, indicating that it may provide therapeutic benefits in managing sepsis-related acute lung injury.
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This study sets out to develop a psycho-social model for assessing the effectiveness of spiritually oriented logotherapy for earthquake victims with PTSD following the 6 February 2023, Kahramanmaraş earthquake in Turkey. The findings of this study will undoubtedly contribute to the development of post-disaster spiritual support services. We developed and implemented a six-week "Psycho-Social Training Programme through Spiritually Oriented Meaning" in the cities of Malatya, Elazığ and Kahramanmaraş, which were significantly affected by the earthquake.

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Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

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This study introduces the spiritual psychological resilience scale (SPRS), a newly developed instrument designed to assess the integration of spiritual beliefs with psychological resilience in the Turkish context. The scale assesses the manner in which individuals draw upon spiritual resources to cope with adversity and maintain psychological well-being. Exploratory and confirmatory factor analyses identified a three-factor structure.

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Background: During the COVID-19 pandemic, health literacy was found to be an asset to manage health-related information. The HLS-COVID-Q22 has been developed to measure COVID-19 health literacy. External validation needs to be assessed in different populations to verify the questionnaire's functioning.

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Simple graphical displays such as icon arrays and tree diagrams have been proposed for communicating health risks and supporting informed decisions. The UK's National Health Service (NHS) uses tree diagrams to communicate the chances of different cervical cancer screening results, but their effectiveness has not been compared to icon arrays. We conducted a well-powered longitudinal experiment involving 3,100 UK women eligible for cervical screening (25-64 years) to examine the effectiveness of icon arrays to communicate possible cervical screening results, relative to the UK NHS's tree diagram and to a numerical-only format.

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Objectives: Despite globally increased attention from policymakers and being recognised as a critical determinant of health, health literacy (HL) research in young people (YP) remains limited. This study aims to describe HL in YP across person factors and explore the associations between HL and health-related quality of life (HRQoL) and the number of visits to general practitioners (GP visits).

Design: Cross-sectional study.

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Fetal alcohol syndrome (FAS) can occur because of high amount of alcohol intake during pregnancy and is characterized by both physical and neurological problems. Children diagnosed with FAS have difficulties in learning, memory, and coordination. Hippocampus has a major role in memory and learning.

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The objective of this study was twofold: firstly, to develop a novel scale for measuring the concept of spiritual leadership, and secondly, to evaluate the psychometric properties of this scale. The principal objective was to facilitate the assessment of spiritual leadership on the part of managerial personnel. In the course of the research, a three-stage process was undertaken.

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Article Synopsis
  • Traumatic brain injury (TBI) is a serious issue that can cause death and make people very sick, affecting not just the brain but also the kidneys and liver.
  • Researchers wanted to study how the body's response to TBI affects these organs, especially by looking at certain markers that show inflammation and cell processes after the injury.
  • In an experiment with mice, they found different reactions in male and female mice's liver and kidney tissues after mild TBI, suggesting that the injury impacts the body in various ways and depends on the sex of the mice.
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Propolis is widely used as a supplementary food product for its health benefits. The aim of this study was to determine the effects of commercial propolis extracts on the liver and kidney. Propolis extracts (250 mg/kgbw/day) were administered orally to adult male rats in solvents of ethanol, propylene glycol, water, and olive oil.

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(1) Background: Dyslipidaemia and insulin resistance are major risk factors for coronary artery disease (CAD). This study investigated the relationship between plasma atherogenic index (PA-I), triglyceride-glucose index (TGI) and other lipid ratios with the presence and prediction of CAD among different age categories. (2) Methods: The study included 223 participants diagnosed with CAD and those with normal coronary arteries (normal group) by coronary computed tomography angiography (CCTA).

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Objectives: The aim of this study was to develop the Motivations for Coping After Disaster Scale. To test the construct validity of the scale, a total of 676 data were collected from three different sampling groups (N1: 388; N2: 194; N3: 94).

Methods: Exploratory Factor Analysis, Confirmatory Factor Analysis (CFA) and Criterion validity analysis were conducted to test the construct validity of the scale.

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Background: During the COVID-19 pandemic, much misinformation and disinformation emerged and spread rapidly via the internet, posing a severe public health challenge. While the need for eHealth literacy (eHL) has been emphasized, few studies have compared the difficulties involved in seeking and using COVID-19 information between adult internet users with low or high eHL.

Objective: This study examines the association between eHL and web-based health information-seeking behaviors among adult Japanese internet users.

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β-Lactams are the most widely used antibiotic family in the world. Nevertheless, they also stand out as the primary culprits for inducing drug hypersensitivity reactions (HSR). Between May 2018 and March 2023, patients with suspected HSRs to β-lactams, who underwent skin tests (ST), were retrospectively screened.

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Introduction: Digital health literacy (DHL) is a key competency for individuals' daily decisions toward their health behavior and wellbeing. While there is much focus on health literacy (HL) among the general population, teachers have been rarely addressed. Given the shortages in the teaching workforce in Europe and the impact of demanding working conditions on their health, it is important to address DHL in teachers.

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Background: A risk-stratified breast screening program could offer low-risk women less screening than is currently offered by the National Health Service. The acceptability of this approach may be enhanced if it corresponds to UK women's screening preferences and values.

Objectives: To elicit and quantify preferences for low-risk screening options.

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Background: Health literacy measurement lays a solid foundation to identify associations with health outcomes and monitor population health literacy levels over time. In mainland China, most existing health literacy instruments are either knowledge-based or practice-based, making health literacy results incomparable between China and other countries. This study aimed to examine the reliability and validity of the 12-item Health Literacy Population Survey (HLS-Q12) in a general population of Chinese adults.

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