Fatty acid addition strategy redirected the metabolic flux towards an ultra-high monensin productivity of .

Monensin, a polyether ionophore antibiotic produced by , exhibits notable anticoccidial and antitumor properties. In this study, a fatty acid addition (FAA) strategy significantly enhanced the monensin production capability of . , resulting in an unprecedented monensin titer of 17.

Low dosage ionic liquid-driven mild and selective lignocellulosic deconstruction of corn stover using biphasic co-solvent systems.

Ionic liquids (ILs) are highly effective in lignocellulose pretreatment due to their excellent solvation properties. However, the single-phase nature of conventional IL pretreatment not only causes component mixing, complicating separation and utilization, but also limits large-scale application due to the high cost. To address these challenges, this study developed a biphasic pretreatment system combining the protic IL [BHEM]mesy with aqueous pentanol, aiming to efficiently fractionate corn stover under mild conditions.

Enhanced Enzymatic Hydrolysis of Tobacco Stalk via Simultaneous Deconstruction and Modification through Triton X-100-mediated Organosolv Pretreatment.

Tobacco stalks (TS) present substantial potential for biofuel and biochemical production; however, their complex lignin structures and tightly bound carbohydrates pose significant challenges for enzymatic hydrolysis due to high recalcitrance. This study explores Triton-X 100-mediated 1,4-butanediol combined with AlCl3 pretreatment for TS fractionation towards improving enzymatic hydrolysis. Optimized pretreatment conditions achieved a significant removal of 87.

Role of in situ surfactant modification of lignin structure and surface properties during glycerol pretreatment in modulating cellulase-lignin binding affinities.

Surfactants are effective agents for enhancing lignocellulosic pretreatment, synergistically modifying lignin with polyols to improve substrate hydrolyzability while achieving comparable delignification. However, the mechanisms underlying the multiple modifications from dual in situ surfactant/polyols grafting that passivate lignin-cellulase interactions and their core affecting factors remain unclear. Following the previously developed polyethylene glycol (PEG) and Triton-assisted pretreatment, the intrinsic correlation among lignin structures, physical barriers, and cellulase interactions was analyzed in this study.

Lignin-based nano-mimetic enzymes: A promising approach for wastewater remediation.

Lignin-based nano-mimetic enzymes have emerged as a promising approach for wastewater remediation, addressing the limitations of conventional treatment methods. This review article explores the potential of lignin, a renewable biomaterial, in developing these novel enzyme-inspired systems. The introduction highlights the rising pollution levels, stricter environmental regulations, and the need for innovative wastewater treatment technologies.

Analysis of the effects of differently charged peptides on α-amylase and their interaction mechanisms.

Nowadays α-amylase is widely used in various fields. Therefore, in this study, the effects of neutral (T), negatively charged (T) and positively charged (T) peptides on α-amylase activity were investigated by means of an applied protein electric field, and spectroscopy and molecular dynamics were employed to investigate this mechanism. It was found that the nature of the charge of the peptides had a strong influence on α-amylase activity, with T and T increasing and decreasing α-amylase activity, respectively, whereas T had no effect on enzyme activity.

In-depth recognition of mixed surfactants maintaining the enzymatic activity of cellulases through stabilization of their spatial structures.

Mixed surfactants improve the enzymatic hydrolysis of lignocellulosic substrates by enhancing cellulase stability against heat, pH, shear, and air-liquid interface stress. Under conditions of multiple factorial stresses (50 °C, pH 4.8, 180 rpm, and 15.

Provincial-scale assessment of vulnerability and resilience to drought in China.

Frequent droughts have caused severe disaster losses in China. Such events can be minimized by enhancing the country's resilience and reducing its vulnerability, where this can ensure socioeconomic stability and sustainable development. Evaluating the vulnerability and resilience to drought is thus crucial for effectively managing the risk of disasters and promoting sustainable socioeconomic development.

Comparative study on liquid versus gas phase hydrochloric acid hydrolysis for microcrystalline cellulose isolation from sugarcane bagasse.

Microcrystalline cellulose (MCC) was successfully synthesized from sugarcane bagasse using a rapid, low-temperature hydrochloric acid (HCl) gas treatment. The primary aim was to develop an energy-efficient "green" cellulose extraction process. Response surface methodology optimized the liquid-phase hydrolysis conditions to 3.

Quantitative correlation analysis between particle liquefaction and saccharification through dynamic changes of slurry rheological behavior and particle characteristics during high-solid enzymatic hydrolysis of sugarcane bagasse.

This study identified the intrinsic relationships among slurry rheology, particle characteristics, and lignocellulosic liquefaction/saccharification based on correlation analysis and principal component analysis during the hydrolysis of sugarcane bagasse pretreated by deep eutectic solvents (DES) and mechanical milling (MM). The DES-MM pretreated lignocellulosic slurry (20% solids) exhibited high apparent viscosity of 1.4 × 10 Pa·s and shear stress of 929.

Lignin derivatives-based hydrogels for biomedical applications.

Recently, numerous studies have been conducted on renewable polymers derived from different natural sources, exploring their suitability for diverse biomedical applications. Lignin as one of the main components of lignocellulosic has garnered significant attention as a promising alternative to petroleum-based polymers. This interest is primarily due to its cost-effectiveness, biocompatibility, eco-friendly nature, as well as its antioxidant and antimicrobial properties.

Biphasic pretreatment excels over conventional sulfuric acid in pinewood biorefinery: An environmental analysis.

This study assesses the environmental impact of pine chip-based biorefinery processes, focusing on bioethanol, xylonic acid, and lignin production. A cradle-to-gate Life Cycle Assessment (LCA) is employed, comparing a novel biphasic pretreatment method (p-toluenesulfonic acid (TsOH)/pentanol, Sc-1) with conventional sulfuric acid pretreatment (HSO, Sc-2). The analysis spans biomass handling, pretreatment, enzymatic hydrolysis, yeast fermentation, and distillation.

Dual assistance of surfactants in glycerol organosolv pretreatment and enzymatic hydrolysis of lignocellulosic biomass for bioethanol production.

This study investigated an innovative strategy of incorporating surfactants into alkaline-catalyzed glycerol pretreatment and enzymatic hydrolysis to improve lignocellulosic biomass (LCB) conversion efficiency. Results revealed that adding 40 mg/g PEG 4000 to the pretreatment at 195 °C obtained the highest glucose yield (84.6%).

Integrated drought vulnerability and risk assessment for future scenarios: An indicator based analysis.

The dynamic interplay between climate change and socioeconomic development has brought about significant changes in drought hazard, vulnerability, and risk within the global socioeconomic system. However, there is a prevailing lack of understanding about how these changes will manifest in an increasingly globalized economy under global warming. To address this knowledge gap, this study utilizes various climatic, geographical, and socioeconomic data from historical period and future projections to comprehensively map and assess the changes in global drought vulnerability and risk of population in the 2030s and 2050s under the SSP126, SSP245, and SSP585 scenarios.

Synthesis of bifunctional thermal response promoters for improved high-solids enzymatic hydrolysis of corncob residues.

The enzymatic hydrolysis cost of lignocellulose can be reduced by improving enzymatic hydrolysis and recycling cellulase by adding additives. A series of copolymers P(SSS-co-SPE) (PSSPs) were synthesized using sodium p-styrene sulfonate (SSS) and sulfobetaine (SPE) as monomers. PSSP exhibited upper critical solution temperature response.

Mapping the field of microalgae CO sequestration: a bibliometric analysis.

Microalgae CO sequestration has gained considerable attention in the last three decades as a promising technology to slow global warming caused by CO emissions. To provide a comprehensive and objective analysis of the research status, hot spots, and frontiers of CO fixation by microalgae, a bibliometric approach was recently chosen for review. In this study, 1561 articles (1991-2022) from the Web of Science (WOS) on microalgae CO sequestration were screened.

Surfactants facilitated glycerol organosolv pretreatment of lignocellulosic biomass by structural modification for co-production of fermentable sugars and highly reactive lignin.

This study reported that surfactants could facilitate the organosolv pretreatment of lignocellulosic biomass (LCB) to produce fermentable sugars and highly active lignin. Under the optimized conditions, the surfactant-assisted glycerol organosolv (saGO) pretreatment achieved 80.7% delignification with a retention of 93.

Enhanced carbon dioxide fixation of Chlorella vulgaris in microalgae reactor loaded with nanofiber membrane carried iron oxide nanoparticles.

To improve the CO dissolution and carbon fixation in the process of microalgae capturing CO from flue gas, a nanofiber membrane containing iron oxide nanoparticles (NPsFeO) for CO adsorption was prepared, and coupled with microalgae utilization to achieve carbon removal. The performance test results showed that the largest specific surface area and pore size were 8.148 m g and 27.

Mussel-inspired lignin decorated cellulose nanocomposite tough organohydrogel sensor with conductive, transparent, strain-sensitive and durable properties.

A novel gel-based wearable sensor with environment resistance (anti-freezing and anti-drying), excellent strength, high sensitivity and self-adhesion was prepared by introducing biomass materials including both lignin and cellulose. The introduction of lignin decorated CNC (L-CNC) to the polymer network acted as nano-fillers to improve the gel's mechanical with high tensile strength (72 KPa at 25 °C, 77 KPa at -20 °C), excellent stretchability (803 % at 25 °C, 722 % at -20 °C). The abundant catechol groups formed in the process of dynamic redox reaction between lignin and ammonium persulfate endowed the gel with robust tissue adhesiveness.

A comprehensive review of lignocellulosic biomass derived materials for water/oil separation.

With rapid socioeconomic development, oil is widely used in all aspects of modern society. However, the extraction, transport, and processing of oil inevitably lead to the production of large quantities of oily wastewater. Traditional oil/water separation strategies are often inefficient, costly, and cumbersome to operate.

Sustainable lignocellulose fractionation by integrating p-toluenesulfonic acid/pentanol pretreatment with mannitol for efficient production of glucose, native-like lignin, and furfural.

A new cutting-edge lignocellulose fractionation technology for the co-production of glucose, native-like lignin, and furfural was introduced using mannitol (MT)-assisted p-toluenesulfonic acid/pentanol pretreatment, as an eco-friendly process. The addition of optimized 5% MT in pretreatment enhanced the delignification rate by 29% and enlarged the surface area and biomass porosity by 1.07-1.

Optimizing tri-acid mixture hydrolysis: An improved strategy for efficient xylooligosaccharides production from corncob.

Propionic acid (PA) hydrolysis of corncob for xylooligosaccharides (XOS) production has the advantages of simple operation, high XOS yield and less by-products, but the high price of PA limits its application. Therefore, partially replacing PA with less expensive organic acids, such as formic acid (FA) and acetic acid (AC), may lower the cost of hydrolysis in XOS production. This work investigated the feasibility of XOS production from corncob using a tri-acid mixture of FA, AC and PA.

Advances in organosolv modified components occurring during the organosolv pretreatment of lignocellulosic biomass.

The valorization of organosolv pretreatment (OP) is a required approach to the industrialization of the current enzyme-mediated lignocellulosic biorefinery. Recent literature has demonstrated that the solvolysis happening in the OP can modify the soluble components into value-added active compounds, namely organosolv modified lignin (OML) and organosolv modified sugars (OMSs), in addition to protecting them against excessive degradation. Among them, the OML is coincidental with the "lignin-first" strategy that should render a highly reactive lignin enriched with β-O-4 linkages and less condensed structure by organosolv grafting, which is desirable for the transformation into phenolic compounds.