Publications by authors named "Fubao Chen"

Recent studies have confirmed the efficacy of sorafenib for patients with advanced renal cell carcinoma; however, its efficacy and safety as an adjuvant therapy in patients with non-metastatic and loco-regional renal cell carcinoma after surgery remains controversial. Thus, the aim of the present retrospective study was to evaluate the efficacy of adjuvant sorafenib therapy in such patients from 8 centers in northwestern China that were treated from August 2009 to December 2016.After surgery, the patients (n = 48) received oral sorafenib for 3 months.

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Purpose: Enhanced recovery after surgery (ERAS) has played an important role in recovery management for radical cystectomy with ileal urinary diversion (RC-IUD). This study is to evaluate ERAS compared with the conventional recovery after surgery (CRAS) for RC-IUD.

Methods: From October 2014 and July 2016, bladder cancer patients scheduled for curative treatment from 25 centers of Chinese Bladder Cancer Consortium were randomly assigned to either ERAS or CRAS group.

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Article Synopsis
  • The study investigates the use of three-dimensional cultures of adipose-derived stem cells (ADSCs) to treat stress urinary incontinence (SUI) in a rat model mimicking menopause and childbirth injury.
  • The researchers created microtissues (MTs) from ADSCs and injected them into SUI-induced rats to assess recovery in voiding function and changes in histology at various time points.
  • Results showed that MTs significantly improved voiding function and histological recovery compared to ADSCs, suggesting that MTs are more effective in treating SUI.
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Article Synopsis
  • The study aimed to assess the diagnosis and treatment of bladder cancer across various centers in China between 2007 and 2012, analyzing a total of 14,260 cases.
  • Results showed that the majority of patients were older males, with urothelial carcinoma being the most prevalent histological type, and non-muscle invasive bladder cancer representing only a small fraction.
  • Treatment approaches varied, with transurethral resection being common for non-muscle invasive cases, while radical cystectomy was primarily used for muscle invasive bladder cancer, highlighting some similarities and differences compared to international practices.
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