Classification of facial diagnosis gloss in Chinese medicine based on different algorithms.

Objective: To design a face gloss classification model and to provide an automatic and quantitative approach for the diagnosis of Chinese medicine (CM) based on the face images.

Methods: To classify the face gloss images into two groups (gloss and non-gloss), feature extraction methods were applied to the original images. The original images were supposed to obtain a more ideal representation in which gloss information was better revealed in four color spaces [including red, green, blue (RGB), hue, saturation, value (HSV), Gray and Lab].

The Metabonomic Studies of Tongue Coating in H. pylori Positive Chronic Gastritis Patients.

In Traditional Chinese Medicine (TCM), tongue diagnosis (TD) has been an important diagnostic method for the last 3000 years. Tongue coating can be used as a very sensitive marker to determine the progress of chronic gastritis. Therefore, the scientific, qualitative, and quantitative study for the pathophysiologic basis of tongue coating (TC) emerged as a major direction for the objective research of TD.

Pulse signal analysis of patients with coronary heart diseases using Hilbert-Huang transformation and time-domain method.

Objective: To explore characteristic of pulse signal to distinguish patients with coronary heart diseases (CHD) from patients without CHD and healthy adults, and accordingly evaluate the potential role of pulse signal to diagnosis CHD.

Methods: Totally 407 patients enrolled from 4 collaborating medical centers were assigned to a CHD group (205 patients) and a non-CHD group (202 patients). The healthy control group (62 adults) enrolled from Shanghai University of Traditional Chinese Medicine.

Computerized tongue image segmentation via the double geo-vector flow.

Background: Visual inspection for tongue analysis is a diagnostic method in traditional Chinese medicine (TCM). Owing to the variations in tongue features, such as color, texture, coating, and shape, it is difficult to precisely extract the tongue region in images. This study aims to quantitatively evaluate tongue diagnosis via automatic tongue segmentation.

The role of central nervous system on hypoglycemia and the feasibility of the brain theory in traditional Chinese medicine on treatment of diabetes mellitus.

The central nervous system (CNS) plays a key regulatory role in glucose homeostasis. In particular, the brain is important in initiating and coordinating protective counterregulatory responses when blood glucose levels fall. This may due to the metabolic dependency of the CNS on glucose, and protection of food supply to the brain.

Metabolic markers and microecological characteristics of tongue coating in patients with chronic gastritis.

Background: In Traditional Chinese Medicine (TCM), tongue diagnosis has been an important diagnostic method for the last 3000 years. Tongue diagnosis is a non-invasive, simple and valuable diagnostic tool. TCM treats the tongue coating on a very sensitive scale that reflects physiological and pathological changes in the organs, especially the spleen and stomach.

Research on zheng classification fusing pulse parameters in coronary heart disease.

This study was conducted to illustrate that nonlinear dynamic variables of Traditional Chinese Medicine (TCM) pulse can improve the performances of TCM Zheng classification models. Pulse recordings of 334 coronary heart disease (CHD) patients and 117 normal subjects were collected in this study. Recurrence quantification analysis (RQA) was employed to acquire nonlinear dynamic variables of pulse.

Computer-assisted lip diagnosis on Traditional Chinese Medicine using multi-class support vector machines.

Background: In Traditional Chinese Medicine (TCM), the lip diagnosis is an important diagnostic method which has a long history and is applied widely. The lip color of a person is considered as a symptom to reflect the physical conditions of organs in the body. However, the traditional diagnostic approach is mainly based on observation by doctor's nude eyes, which is non-quantitative and subjective.

[Metabolite changes in the greasy tongue coating of patients with chronic gastritis].

Objective: To explore the changes in metabolites in the greasy tongue coating in patients with chronic gastritis.

Methods: Forty chronic gastritis patients presenting with greasy tongue coating, 30 chronic gastritis patients presenting with non-greasy tongue coating, and 20 healthy control persons presenting with light red tongues and thin white coating were enrolled, and the tongue coating was detected by combining artificial diagnosis and the Z-BOX Tongue Digital Analyzer's diagnosis. Samples of all the tongue coatings were collected before treatment.

Study on intelligent syndrome differentiation in traditional Chinese medicine based on multiple information fusion methods.

Numerous researchers have taken the solid step forward towards the objectification research of Traditional Chinese Medicine (TCM) four diagnostic methods. However, it is deficient in studies on information fusion of the four diagnostic methods. We establish four-diagnosis syndrome differentiation model of TCM based on information fusion technology.

[Feature extraction and recognition of traditional Chinese medicine pulse based on hemodynamic principles].

In this paper, factors contributing to the formation of pulse wave were analyzed based on hemodynamic principles. It is considered that formation of pulse wave was related to its propagation and reflection characteristics. Propagation of the pulse wave was characterized by pulse wave velocity, and reflection of the pulse wave was characterized by reflection coefficient.

[Development and evaluation of an inquiry scale for diagnosis of heart system syndromes in traditional Chinese medicine].

Objective: To develop an inquiry scale for diagnosis of heart system syndromes, and to discuss the provisional standardization of the inquiry method in traditional Chinese medicine (TCM).

Methods: Based on scale-making method, Chinese medicine theory and literature searching, an inquiry scale for diagnosis of heart system syndromes in TCM was developed. Statistics method, frequency counting and Delphi method were used for analysis.

Tracheal compliance and limit flow rate changes in a murine model of asthma.

Trachea is the unique passage for air to flow in and out. Its tone is of importance for the respiration system. However, investigation on how tracheal tone changes due to asthma is limited.

Evaluation of multislice computed tomographic perfusion imaging and computed tomographic angiography on traumatic cerebral infarction.

Objective: To evaluate the application value of multislice computed tomographic perfusion imaging (MSCTPI) and multislice computed tomographic angiography (MSCTA) on traumatic cerebral infarction.

Methods: MSCTA was performed on 10 patients who were initially diagnosed as traumatic cerebral infarction by normal conventional computed tomography (NCCT), among whom, 3 patients were examined by MSCTPI simultaneously. Reconstructed images of the intracranial artery were made with techniques of maximum intensity projection (MIP) and volume rendering (VR) from MSCTA scanning data.

[Serum proteomics study of chronic gastritis with dampness syndrome in traditional Chinese medicine].

Objective: To explore microcosmic information in chronic gastritis dampness syndrome by using serum proteomics of patients with chronic gastritis dampness syndrome.

Methods: Serum proteomics of 18 dampness syndrome cases, 17 non-dampness syndrome cases in chronic gastritis patients and 8 normal controls were analyzed by surface enhanced laser desorption/ionization-time of flight (SELDI-TOF) protein-chip.

Results: There was a high expression trend in three ratios of charge (of an electron) to mass (M/S) of 3.

[Immunological mechanism of exfoliative tongue fur in children with asthma].

Objective: To explore the immunological mechanism of exfoliative tongue fur in children with asthma.

Methods: Thirty-nine children with asthma, twenty-eight children with repetitive respiratory tract infection (non-asthma) and eleven healthy children were divided into five groups, which were asthma with exfoliative fur or with non-exfoliative fur groups, non-asthma with exfoliative fur or with non-exfoliative fur groups and normal control group. The concentrations of keratin 13 and bcl-2 in cells exfoliated from tongue fur were detected by immunohistochemical method.