Publications by authors named "Fu-chun Chen"

Inflammatory responses play significant role in infectious etiology-induced acute lung injury (ALI). Histone deacetylase 2 is found to be essential and stimulated in lipopolysaccharide (LPS)-induced ALI by regulating proinflammatory cytokines. miR-23b has been demonstrated to be downregulated in LPS-induced inflammatory injury.

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Background: The few previous studies that focused on the effects of compression garments (CG) on distance running performance have simultaneously measured electromyogram, physiological, and perceptual parameters. Therefore, this study investigated the effects of CG on muscle activation and median frequency during and after distance running, as well as blood-lactate concentration and rating of perceived exertion (RPE) during distance running.

Methods: Eight healthy male recreational runners were recruited to randomly perform two 40 min treadmill running trials, one with CG, and the other with control garment made of normal cloth.

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Metal oxides have attracted substantial attention over the years and are commonly used in the semiconductor industry because of their excellent physical and chemical properties. Among the various metal oxides, cuprous oxide (CuO) is regarded as a promising material. It is inexpensive, earth-abundant, and nontoxic; therefore, it can be used in catalysis, sensors, solar cells, and p-type semiconductors.

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Heterogeneous nanoparticles are widely used in catalysis, sensors and biology due to their versatile functions. Among the various heterogeneous nanoparticles, Au-Cu2O core-shell nanoparticles show high stability and short response times for use as sensors and catalysts and have thus attracted much attention. Previous studies show that the properties of Au-Cu2O are mainly related to the shape and size of the Au-Cu2O nanoparticles.

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This pilot study retrospectively investigated the feasible effect and safety of neuromuscular electrical stimulation (NMES) for the management of neuropathic pain (NPP) caused by spinal cord injury (SCI).A total of 54 patient cases with NPP after SCI were included. Of these, 27 cases underwent carbamazepine plus NMES treatment, and were assigned to an NMES group; while the other 27 cases received carbamazepine only, and were assigned to a control group.

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This study investigated the effect of transcutaneous electrical nerve stimulation (TENS) for the treatment of patients with chronic pain after ankylosing spondylitis (AS).A total of 72 eligible patients with chronic pain following AS were included. All included patients received exercise and were assigned to a treatment group and a control group equally.

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Article Synopsis
  • The study focuses on the importance of detecting EGFR mutations for treatment decisions in non-small cell lung cancer (NSCLC) patients and introduces a new testing method called quantum dots immunofluorescence histochemistry (QDs-IHC).
  • Researchers compared QDs-IHC with traditional immunohistochemistry (IHC) and amplification refractory mutation system (ARMS) on 65 NSCLC cases, finding that QDs-IHC had a sensitivity of 86.7% and specificity of 100%.
  • The findings suggest that QDs-IHC is an effective, standardized method for detecting EGFR mutations with high sensitivity and specificity, which could aid in diagnosing and treating lung cancer more
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Background: This study aimed to examine the correlation of heart rate variability (HRV) and meridian electrical conductance among middle-aged women during an 8-week period of auricular acupressure (AA) treatment for weight reduction.

Methods: Sixty (60) subjects were randomized either to a control group (n=30) or to a treatment group with AA (n=30). Anthropometric parameters, HRV indices, and meridian levels were measured before treatment, at the 5th week, and 1 week after the 8-week treatment period.

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Objective: To investigate the dynamic expression of cyclooxygenase-2 (COX-2) and caspase-3 during the carcinogenesis, invasion and metastasis of 3-methylcholanthrene (MCA) and diethylnitrosamine (DEN)-induced rat lung cancer and its significance.

Methods: Iodized oil with MCA and DEN was instilled into the left bronchi of 80 Wistar rats to induce squamous cell lung carcinoma. Iodized oil without MCA and DEN was instilled into the left bronchi of 10 rats as control group.

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