Characterization of bloom formation on open sun-dried squid (Illex argentinus): A chemical composition perspective.

A modified intermittent sun-drying process was conducted to investigate the mechanism and chemical composition of bloom formation on dried squid (Illex argentinus). The bloom layer on the squid surface consisted of free amino acids and fat. Fat and free amino acid components were extracted and analyzed using SEM-EDX, FT-IR, GC, and HPLC.

Vascular endothelial growth factor pathway's influence on bevacizumab efficacy in metastatic colorectal cancer treatment.

In this article, an article published in the , which focuses on whether the expression of programmed death-ligand 1 (PD-L1) affects the effectiveness of chemotherapy regimens, including bevacizumab, in treating patients with colorectal cancer (CRC). Through neutralization of vascular endothelial growth factor (VEGF), bevacizumab inhibits tumor angiogenesis, impairing neovascularization and thereby depriving the tumor of essential nutrients and oxygen. Conversely, PD-L1 binding to VEGF receptor 2 promotes angiogenesis, supporting tumor vasculature.