Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-κB signaling pathway.

Background: Neuroinflammation is closely associated with functional outcome in subarachnoid hemorrhage (SAH) patients. Our recent study demonstrated that fluoxetine inhibited NLRP3 inflammasome activation and attenuated necrotic cell death in early brain injury after SAH, while the effects and potential mechanisms of fluoxetine on neuroinflammation after SAH have not been well-studied yet.

Methods: One hundred and fifty-three male SD rats were subjected to the endovascular perforation model of SAH.

[Influence of Biochar on Greenhouse Gases Emissions and Physico-chemical Properties of Loess Soil].

Biochar is known to be a good soil amendment to improve soil physical and biochemical characteristics, to increase crop yield, and to mitigate greenhouse gas emissions from soils. In this study, five addition levels of apple tree branches-derived biochar (0, 20, 40, 60, 80 t·hm) were used in field plot test. The effects of biochar on soil temperature, soil aggregates, NO-N, NH-N, microbial biomass carbon and greenhouse gas fluxes were investigated during the whole pepper growth season.

Transplantation of Flk-1+ human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and anti-inflammatory and angiogenesis effects in an intracerebral hemorrhage rat model.

Mesenchymal stem cells (MSCs) have been successfully used for the treatment of experimental intracerebral hemorrhage (ICH). However, the neuroprotective mechanisms through which MSCs improve neurological functional recovery are not fully understood. In the present study, we tested the hypothesis that treatment with MSCs inhibits inflammation after ICH and reduces subsequent brain injury.

Positive and negative photoion spectroscopy study of monochlorothiophenes.

Photolysis dynamics of monochlorothiophenes (2- and 3-chlorothiophenes) is investigated using positive and negative photoion mass spectrometry combined with the synchrotron vacuum ultraviolet radiation. A dozen of the daughter cations are observed in the time-of-flight mass spectra, and their appearance energies are determined by the photoion efficiency spectroscopy measurements. At the energetic threshold, the concerted process rather than a stepwise reaction for C(4)H(3)SCl(+) → C(2)HSCl(+) + C(2)H(2) and the ring-open isomers of the dehydrogenated thiophene cations (C(4)H(3)S(+) and C(4)H(2)S(+)) formed in C(4)H(3)SCl(+) → C(4)H(3)S(+) + Cl and C(4)H(2)S(+) + HCl are proposed on the basis of the B3LYP/6-311+G(3df,3pd) calculations.

Vacuum ultraviolet negative photoion spectroscopy of chloroform.

Negative ions Cl(-), Cl(2)(-), CCl(-), CHCl(-), and CCl(2)(-) are observed in vacuum-ultraviolet ion-pair photodissociations of chloroform (CCl(3)H) using the Hefei synchrotron radiation facility, and their ion production efficiency curves are recorded in the photon energy range of 10.00-21.50 eV.

[Occult hepatitis B virus infection in chronic viral hepatitis patients with non-A to E hepatitis virus infection].

Objective: To observe the status of occult hepatitis B virus infection in chronic viral hepatitis patients with non-A to E hepatitis virus infection and explore the diagnostic value of fluorescence quantitative polymerase chain reaction (FQ-PCR) technique for occult hepatitis B virus infection.

Methods: The amount of HBV-DNA in serum and liver tissue from 57 patients with non-A to E hepatitis virus infection who were diagnosed as chronic viral hepatitis by Menghini method liver biopsy were detected by using FQ-PCR technique, then the relation between the viral load of HBV DNA in liver tissue and hepatic inflammatory activity were analyzed.

Results: Thirteen (22.

Does the incoming oxygen atom influence the geometries and the electronic and magnetic structures of Co(n) clusters?

The small-sized Co(n)O (n = 1-5) clusters with different spin states have been systematically investigated by using the density-functional approach. The total energies, equilibrium geometries, and magnetic properties are discussed. Equilibrium geometries and the relative stabilities in terms of the calculated fragmentation energies are discussed, manifesting that the remarkable stable small-sized cluster corresponds to the Co(2)O isomer, and that the O atom prefers the surface-capped pattern on Co(n) (n > 2) clusters and bonds with three Co atoms simultaneously.

[Electron temperature of Al plasma estimated with Ar].

Protected with Ar, it would induce atom Ar breakdown to ablate aluminum target with a pulsed Nd: YAG laser beam. Further more, a lot of Ar+ ionic characteristic lines radiation appeared accompanying the aluminum plasma emission. In this work, based on the Ar+ ionic characteristic lines radiation, we analyzed time-resolved behavior of four Ar+ ionic characteristic lines Ar II 385.