Publications by authors named "Fu-Rong Fan"
Rationale: Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a rare autoimmune disease of the central nervous system that affects the meninges, brain, spinal cord, and optic nerves. GFAP astrocytopathy can coexist with a variety of antibodies, which is known as overlap syndrome. Anti-NMDAR-positive encephalitis overlap syndrome has been reported; however, encephalitis overlap syndrome with both anti-NMDAR and sulfatide-IgG positivity has not been reported.
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- - Rheumatoid arthritis (RA) and primary Sjögren's syndrome (pSS) are common autoimmune diseases that often occur together, but their shared mechanisms are not fully understood.
- - This study employed bioinformatic analyses to identify common genes, microRNAs, and potential therapeutic drugs associated with both diseases, focusing on gene co-expression patterns and public disease databases.
- - Key findings included identifying four hub genes (CXCL10, GZMA, ITGA4, PSMB9) and suggesting 24 potential drugs, including some already known for treating RA and pSS, with hsa-mir-21 identified as a significant microRNA in their shared mechanisms.
Hematomyelia associated with coronavirus disease 2019: A rare case report.
Medicine (Baltimore)
July 2023
Rationale: Coronavirus disease 2019 (COVID-19) can damage the central nervous system. Although there have been reports of cerebral hemorrhage and infarction caused by COVID-19, hematomyelia due to COVID-19 has never been reported.
Patient Concerns: A 40-year-old male was admitted to the hospital with positive nucleic acid detection for COVID-19 after experiencing fever for 2 weeks, urinary retention, fecal retention, and pain in both lower extremities for a week.