Publications by authors named "Fu-Niu Qin"
Receptivity is a limited time in which uterine endometrium can establish a successful dialogue with blastocyst. This study was to investigate the effect of asynchronous embryo transfer on uterine receptivity in mice. Embryos under different stages were transferred into two oviduct sides of a recipient mouse on day 1 of pseudopregnancy.
View Article and Find Full Text PDFThe prevalence of diabetes is increasing worldwide with the trend of patients being young and creating a significant burden on health systems, including reproductive problems, but the effects of diabetes on embryo implantation are still poorly understood. Our study was to examine effects of diabetes on mouse embryo implantation, providing experimental basis for treating diabetes and its complications. Streptozotocin (STZ) was applied to induce type 1 diabetes from day 2 of pregnancy or pseudopregnancy in mice.
View Article and Find Full Text PDFArticle Synopsis
- Embryo implantation requires a specific interaction between the uterus and the blastocyst, driven by complex molecular networks.
- Snail, a transcription repressor, is highly expressed in the implantation site and appears to influence other implantation-related genes.
- The study found that Snail's expression is significantly induced by HB-EGF via the EGFR-ERK-Stat3 pathway, indicating a connection with Cox-2 and suggesting its role in embryo implantation and decidualization in mice.