HOXA11-AS aggravates microglia-induced neuroinflammation after traumatic brain injury.

Long noncoding RNAs (lncRNAs) participate in many pathophysiological processes after traumatic brain injury by mediating neuroinflammation and apoptosis. Homeobox A11 antisense RNA (HOXA11-AS) is a member of the lncRNA family that has been reported to participate in many inflammatory reactions; however, its role in traumatic brain injury remains unclear. In this study, we established rat models of traumatic brain injury using a weight-drop hitting device and injected LV-HOXA11-AS into the right lateral ventricle 2 weeks before modeling.

Laminoplasty using the Posterior Midline Approach in the Treatment of C1-2 Spinal Tumors.

Aim: This study aimed to investigate the method and efficacy of vertebral reconstruction using the posterior midline approach (PMA) in the treatment of C1-2 spinal tumors.

Material And Methods: Twenty-seven patients with C1-2 spinal tumors from the Affiliated Hospital of Luzhou Medical College, who underwent microsurgical tumor resection through an occipitocervical PMA and spinal reset-reconstruction from January 2007 to December 2013, were enrolled in the study. The clinical data and results of these patients were analyzed and summarized.