Neutral mononuclear indium(III) photosensitizers for CO photoreduction.

Herein, neutral mononuclear indium(III) complexes (In-1-In-3) containing 2,6-di(1-pyrrol-2-yl)pyridine and substituted dipyridylpyrrole pincer ligand were employed as photosensitizers (PS) in photocatalytic CO reduction. In-2 exhibits good photo-activity and selectivity, which is superior to the classic PS Ru(bpy). The amount of CO generation is 28.

Mononuclear indium(III) photosensitizers for photo-dehalogenation and olefin reduction.

Photoactive main-group complexes have been relatively underexplored in photocatalytic applications. Herein, we report a family of indium(III) complexes (In-1-In-4) containing pyridylpyrrolide ligands with different amounts of methyl groups, which all exhibit intense visible-light absorption as well as blue-green emission with nanosecond emission lifetimes and emission quantum yields of 6.7-12.

Homoleptic Al(III) Photosensitizers for Durable CO Photoreduction.

Exploiting noble-metal-free systems for high-performance photocatalytic CO reduction still presents a key challenge, partially due to the long-standing difficulties in developing potent and durable earth-abundant photosensitizers. Therefore, based on the very cheap aluminum metal, we have deployed a systematic series of homoleptic Al(III) photosensitizers featuring 2-pyridylpyrrolide ligands for CO photoreduction. The combined studies of steady-state and time-resolved spectroscopy as well as quantum chemical calculations demonstrate that in anerobic CHCN solutions at room temperature, visible-light excitation of the Al(III) photosensitizers leads to an efficient population of singlet excited states with nanosecond-scale lifetimes and notable emission quantum yields (10-40%).

In Vitro Anti-Toxoplasma gondii Activity Evaluation of a New Series of Quinazolin-4(3H)-one Derivatives.

Toxoplasmosis post serious threaten to human health, leading to severely eye and brain disease, especially for immunocompromised patients and pregnant women. The multiple side effects and long dosing period of current main treatment regiments calls for high effective and low toxicity anti-toxoplasmosis drugs. Herein, we report our efforts to synthesize a series of 2-(piperazin-1-yl)quinazolin-4(3H)-one derivatives and investigate their activity against Toxoplasma gondii tachyzoites in vitro based on cell phenotype screening.

Semi-synthesis, antibacterial activity, and molecular docking study of novel pleuromutilin derivatives bearing cinnamic acids moieties.

To develop new antibiotics owning a special mechanism, we used the molecular assembly method to synthesize a series of novel pleuromutilin derivatives containing a cinnamic acid scaffold at the C-14 side chain. We evaluated their antibacterial activity and used in silico molecular docking to study their binding mode with the target. The structure-activity relationship (SAR) study suggested that compounds with NO (13e), OH (13u), and NH (13y) appeared more active (0.

Complete Genome Sequence of Trueperella pyogenes, Isolated from Infected Farmland Goats.

Trueperella pyogenes is a significant pathogen of livestock, causing diverse diseases, such as mastitis, liver abscessation, and pneumonia. In this study, we have reported the genome sequence of Trueperella pyogenes 2012CQ-ZSH. Moreover, several genes coding for virulence factors were found, such as pyolysin (PYO), nanH, nanP, cbpA, fimC, and fimE.

A simple and rapid method for detection of Goose Parvovirus in the field by loop-mediated isothermal amplification.

Background: Goose parvovirus (GPV) is a Dependovirus associated with latent infection and mortality in geese. Currently, in a worldwide scale, GPV severely affects geese production. The objective of this study is to develop a loop-mediated isothermal amplification (LAMP) method for the sensitive, rapid, and inexpensive detection of GPV in the field.