Iron-Rich Conditions Induce OmpA and Virulence Changes of .

Iron ions affect the expression of outer membrane protein A (OmpA), a major pathogenic protein in To analyze the effect of iron ions on the expression of the OmpA protein of and explore its association with the virulence of OmpA. Site-directed mutagenesis was used to construct gene deletion strains and gene repair strains. The OmpA protein expression of under culture with different contents of iron ions was detected.

Biofilm-Related Genes: Analyses in Multi-Antibiotic Resistant Acinetobacter Baumannii Isolates From Mainland China.

BACKGROUND Acinetobacter baumannii is an important nosocomial pathogen which shows a high level of mortality risk. Several papers have reported biofilm formation as a well-known pathogenic mechanism in A. baumannii infections and exceptional antibiotic resistance.