Global phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis.

Syphilis, which is caused by the sexually transmitted bacterium Treponema pallidum subsp. pallidum, has an estimated 6.3 million cases worldwide per annum.

Seroprevalence of anti- IgM in neonatal respiratory tract infections in Hungary.

To determine the seroprevalence of specific IgM indicative of respiratory tract infection (RTI) due to (CT) among symptomatic infants. A descriptive study was conducted on young infants up to 5 months old at the Bacterial Sexually Transmitted Infections Reference Laboratory, National Centre for Epidemiology, Budapest, covering the period 2008-2016. Serum samples from infants suffering from RTIs were screened with a micro-immunofluorescence test (Focus, Cypress, USA) for the presence of anti-specific IgM.

Distribution of Chlamydia trachomatis genotypes in neonatal conjunctivitis in Hungary.

The objective of the present study was to determine the frequency and age distribution of different Chlamydia trachomatis (CT) genotypes causing ophthalmia neonatorum (ON) in Hungary. Using CT specific PCR, we tested 76 conjunctival samples from symptomatic infants up to 3 months old in the National Centre for Epidemiology, Budapest between 2008 and 2016. CT tested positive in 30 of 76 conjunctival samples (39.

Emergence of the lymphogranuloma venereum L2c genovariant, Hungary, 2012 to 2016.

In eastern Europe, few countries have so far reported laboratory-confirmed cases of lymphogranuloma venereum (LGV). Here we describe 22 LGV cases in men who have sex with men (MSM) detected in Hungary from November 2012 to July 2016. Sequence analyses show that 16 of these 22 cases were affected by the L2c genovariant, with from 2012 to 2014, one LGV L2c case detected per year, followed by seven cases in 2015 and six up to July 2016.

Chlamydial conjunctivitis: prevalence and serovar distribution of Chlamydia trachomatis in adults.

The extragenital manifestation of Chlamydia trachomatis infection frequently results in non-specific conjunctivitis among sexually active adults. The aims of the present study were to determine the prevalence of C. trachomatis, to describe the distribution of serovars among patients with conjunctivitis and to characterize the relationship between the prevalence and patient demographics such as age and gender.

[Ornithosis--case report and current concerns].

The authors describe a severe case of psittacosis requiring intensive care, and summarize the potential means of diagnosis, as well as the epidemiologic and therapeutic aspects of the disease. Clinical signs of ornithosis do not allow a reliable differentiation from other atypical bacterial infections, thus, exploring the possible exposure to birds in the patient's history is most important in these cases. Knowledge of bird exposure in the history leads the clinician to the correct diagnosis that may result quick recovery due to the adequate therapy.

Genotyping of Chlamydia trachomatis from the endocervical specimens of high-risk women in Hungary.

The distribution of different Chlamydia trachomatis serovars in Hungary has not been reported previously. The objective of this study was to determine the distribution and prevalence of C. trachomatis serovars in a high-risk population by genotyping.

Two fatal cases of psittacosis caused by Chlamydophila psittaci.

Two fatal cases of psittacosis are described in two poultry-processing-plant employees presenting with pneumonia and respiratory failure. Diagnosis was confirmed by serological and PCR methods. Psittacosis due to Chlamydophila psittaci infection usually has a good recovery rate, although diagnostic delay and mistreatment can lead to severe complications and even death.

Chronic infections and genetic factors in the development of ischemic stroke.

The aim of this study was to examine whether chronic infections and genetic factors of the host play roles in the pathophysiology of acute noncardioembolic ischemic stroke. Blood samples from 59 subjects with ischemic stroke and 52 control patients were investigated by nested PCR for the presence of C. pneumoniae DNA, HCMV DNA and enterovirus RNA, by ELISA for the levels of antibodies to C.