Publications by Frinto Francis

Publications by authors named "Frinto Francis"

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Dry Powder Inhalation of Nintedanib in Dibasic Calcium Phosphate for Targeting the Lungs in Pulmonary Fibrosis.

Sanjay Singh Frinto Francis Mohit Barsain Naresh Kothuri Sonia Verma

Mol Pharm

March 2025

We prepared three variants of nintedanib dry powder inhalations (DPIs), one with dibasic calcium phosphate dihydrate (CaHPO·2HO) and two with lactose monohydrate as the carrier. CaHPO is not reported as a DPI excipient. We compared nintedanib pharmacokinetics and efficacy of the CaHPO formulation against bleomycin-induced pulmonary fibrosis following oral (3.

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