Publications by authors named "Friedmann D"

Objectives: This work highlights the methods used to develop a multi-pulse 1726 nm laser system combined with bulk air-cooling for selective sebaceous gland (SG) photothermolysis using thermal imaging and software algorithms. This approach enables treating to a desired tissue temperature and depth to provide a safe, effective, reproducible, and durable treatment of acne.

Methods: We designed and built a 1726 nm laser system with a 40 W maximum power output, a highly controlled air-cooling device, and a thermal camera in the handpiece, which permits real-time temperature monitoring of the epidermis.

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Biparietal osteodystrophy, also known as biparietal thinning, is an uncommon illness that causes symmetrical thinning of the parietal bones. It primarily affects women in their sixth and seventh decades of life. We present a case of a 73-year-old female with osteoporosis and osteoarthritis who visited a dermatology clinic with a bulging mass around her vertex scalp, accompanied by episodes of dizziness and blurred vision.

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This study examines the efficacy of jaw exercising products for facial contouring. The two individuals used a commercially available jaw exerciser for approximately three months, following the provided instructions. Neither case reported noticeable changes in jaw appearance based on subjective measurements.

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Papulopustular rosacea is an inflammatory subtype of rosacea that can significantly impair patients' quality of life. Available treatment options range from anti-inflammatory topical and oral medications to laser and light therapies. Photodynamic therapy with aminolevulinic acid (ALA-PDT) has emerged as a more recent treatment option for papulopustular rosacea.

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Article Synopsis
  • This study explores the outcomes and management of pediatric auditory brainstem implantation (ABI) for children with severe inner ear malformations, aiming to unify clinical practices and address current challenges.
  • A systematic review of relevant findings from the Third International Pediatric ABI Symposium analyzed data from multiple countries, highlighting trends in auditory outcomes, surgical approaches, and rehabilitation strategies.
  • Key conclusions emphasize the need for standardized guidelines and improved collaboration among healthcare professionals to enhance patient outcomes and guide future research in this specialized field.
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Background: Cosmetically unappealing temporal volume loss can develop as a result of facial aging.

Objective:  To present an evidenced-based approach towards safe and effective temple filling.

Methods: We review the underlying anatomy of the temple and optimal anatomy-driven injection techniques associated with temple volumization.

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  • Microneedling is a popular and minimally invasive skin rejuvenation technique, but rare granulomatous reactions have been documented following the procedure.
  • This study systematically reviewed existing literature and identified 13 studies involving 15 patients aged 26-74 who experienced non-necrotizing granulomatous inflammation post-procedure, often linked to motorized microneedling and Vitamin C use.
  • Treatment options varied and had inconsistent success, with no clear standard approach, highlighting that these reactions can be difficult to manage.
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Background: For three decades, fractional ablative CO lasers have been used for skin rejuvenation. With breakthroughs in laser technology and expanding popularity, new recommendations and suggestions arise on a regular basis.

Objective: To develop up-to-date clinical recommendations on safety measures, therapeutic framework, and techniques to improve treatment outcomes.

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Serotonin neurons from the raphe nuclei project across the entire brain and modulate diverse physiology and behavior by acting on over a dozen receptors. Here, we took a step towards dissecting this complex process by examining the effects of agonists and antagonists of four widely expressed serotonin receptors (2A, 2C, 1A, and 1B) on spontaneous mouse behavior, which we related to time-integrated whole-brain neuronal activity as assessed by the expression of Fos, a canonical immediate-early gene product. Low-dimensional representations of behavioral and Fos map data revealed the dominant factors of variation in each domain, captured predictable differences across drug groups, and enabled predictions of behavioral changes following perturbations in Fos maps and vice versa.

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  • The study aims to describe the cochlear apex's anatomy to assist surgeons during apical electrode placement for cochlear implants, enhancing procedural success.
  • Utilizing a retrospective analysis of 82 CT scans, the researchers measured distances from key middle ear landmarks to the cochlear apex, finding significant variability in anatomy.
  • A new "stapes vector" was identified as a reliable reference point for locating the cochlear apex, which could improve surgical accuracy and minimize damage during procedures.
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  • The study aimed to evaluate cochlear implant performance after patients underwent reimplantation using a different manufacturer's device.
  • A total of 29 patients were analyzed, showing a drop in average CNC speech recognition scores before reimplantation but a recovery to comparable levels following the procedure.
  • The findings indicate that reimplantation with a new device can lead to similar speech recognition performance as the original device, without significant statistical differences in outcomes.
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Objective: To characterize transimpedance matrix (TIM) heatmap patterns in patients at risk of labyrinthine abnormality to better understand accuracy and possible TIM limitations.

Study Design: Retrospective review of TIM patterns, preoperative, and postoperative imaging.

Setting: Tertiary referral center.

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Hearing loss is common among Veterans, and extensive hearing care resources are prioritized within the Veterans Administration (VA). Severe hearing loss poses unique communication challenges with speech understanding that may not be overcome with amplification. We analyzed data from the VA Audiometric Repository between 2005 and 2017 and the relationship between hearing loss severity with speech recognition scores.

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  • - Extramammary Paget's disease (EMPD) is a rare skin cancer classified as primary (without an internal malignancy) or secondary (linked to another cancer), with this case report detailing a patient who developed primary EMPD 10 years after having secondary EMPD in the same area.
  • - The patient underwent a wide local excision for the secondary cervical EMPD, and subsequent analysis confirmed the emergence of primary EMPD, raising questions about the underlying causes like field cancerization or risk factors.
  • - The report emphasizes the necessity of long-term follow-up care and the efficacy of Mohs micrographic surgery as the best treatment option for EMPD, highlighting the importance of careful diagnostics and monitoring for these patients.
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Background: Lower extremity reticular and telangiectatic veins are of common cosmetic concern.

Objective: To retrospectively evaluate results of lower extremity sclerotherapy using a combination of foam and liquid sclerosing agents.

Methods: A retrospective chart review of sclerotherapy patients at a dermatology practice (January 2014 to April 2023) was performed.

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