Objectives: This work highlights the methods used to develop a multi-pulse 1726 nm laser system combined with bulk air-cooling for selective sebaceous gland (SG) photothermolysis using thermal imaging and software algorithms. This approach enables treating to a desired tissue temperature and depth to provide a safe, effective, reproducible, and durable treatment of acne.
Methods: We designed and built a 1726 nm laser system with a 40 W maximum power output, a highly controlled air-cooling device, and a thermal camera in the handpiece, which permits real-time temperature monitoring of the epidermis.
Biparietal osteodystrophy, also known as biparietal thinning, is an uncommon illness that causes symmetrical thinning of the parietal bones. It primarily affects women in their sixth and seventh decades of life. We present a case of a 73-year-old female with osteoporosis and osteoarthritis who visited a dermatology clinic with a bulging mass around her vertex scalp, accompanied by episodes of dizziness and blurred vision.
View Article and Find Full Text PDFThis study examines the efficacy of jaw exercising products for facial contouring. The two individuals used a commercially available jaw exerciser for approximately three months, following the provided instructions. Neither case reported noticeable changes in jaw appearance based on subjective measurements.
View Article and Find Full Text PDFPapulopustular rosacea is an inflammatory subtype of rosacea that can significantly impair patients' quality of life. Available treatment options range from anti-inflammatory topical and oral medications to laser and light therapies. Photodynamic therapy with aminolevulinic acid (ALA-PDT) has emerged as a more recent treatment option for papulopustular rosacea.
View Article and Find Full Text PDFBackground: Cosmetically unappealing temporal volume loss can develop as a result of facial aging.
Objective: To present an evidenced-based approach towards safe and effective temple filling.
Methods: We review the underlying anatomy of the temple and optimal anatomy-driven injection techniques associated with temple volumization.
Background: For three decades, fractional ablative CO lasers have been used for skin rejuvenation. With breakthroughs in laser technology and expanding popularity, new recommendations and suggestions arise on a regular basis.
Objective: To develop up-to-date clinical recommendations on safety measures, therapeutic framework, and techniques to improve treatment outcomes.
Serotonin neurons from the raphe nuclei project across the entire brain and modulate diverse physiology and behavior by acting on over a dozen receptors. Here, we took a step towards dissecting this complex process by examining the effects of agonists and antagonists of four widely expressed serotonin receptors (2A, 2C, 1A, and 1B) on spontaneous mouse behavior, which we related to time-integrated whole-brain neuronal activity as assessed by the expression of Fos, a canonical immediate-early gene product. Low-dimensional representations of behavioral and Fos map data revealed the dominant factors of variation in each domain, captured predictable differences across drug groups, and enabled predictions of behavioral changes following perturbations in Fos maps and vice versa.
View Article and Find Full Text PDFOtol Neurotol Open
September 2024
J Vasc Surg Cases Innov Tech
December 2024
Objective: To characterize transimpedance matrix (TIM) heatmap patterns in patients at risk of labyrinthine abnormality to better understand accuracy and possible TIM limitations.
Study Design: Retrospective review of TIM patterns, preoperative, and postoperative imaging.
Setting: Tertiary referral center.
Hearing loss is common among Veterans, and extensive hearing care resources are prioritized within the Veterans Administration (VA). Severe hearing loss poses unique communication challenges with speech understanding that may not be overcome with amplification. We analyzed data from the VA Audiometric Repository between 2005 and 2017 and the relationship between hearing loss severity with speech recognition scores.
View Article and Find Full Text PDFBackground: Lower extremity reticular and telangiectatic veins are of common cosmetic concern.
Objective: To retrospectively evaluate results of lower extremity sclerotherapy using a combination of foam and liquid sclerosing agents.
Methods: A retrospective chart review of sclerotherapy patients at a dermatology practice (January 2014 to April 2023) was performed.