Antibacterial Effect and Substantivity of Toothpaste Slurries In Vivo.

Purpose: This double-blind, clinical, cross-over study evaluated the antibacterial effect of three toothpastes (ASF, HTP and STP) and a chlorhexidine mouthrinse (0.2%; CHX; positive control) after a single application on established biofilm over a period of 24 h (substantivity).

Materials And Methods: Twenty-four subjects refrained from all oral hygiene measures for a period of 72 h.