Publications by authors named "Fried T"

Interviews with 22 home-based primary care (HBPC) clinicians revealed that infectious disease physicians and clinical pharmacists facilitate infection management and antibiotic selection, respectively, and that local initiatives within programs support antibiotic prescribing decisions. Interventions that facilitate specialist engagement and tailored approaches that address the unique challenges of HBPC are needed.

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Uncertainty lies at the heart of everyday choices, affecting both decisions about precise quantities and those with less tangible, more qualitative, outcomes. Previous literature on decisions under uncertainty focused on alternatives with quantifiable outcomes, for example monetary lotteries. In such scenarios, decision-makers make decisions based on success chance, outcome magnitude, and individual preferences for uncertainty.

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Objective: The objective of this study was to examine weight reduction and adverse events associated with use of antiobesity medications (AOMs) in older adults ages ≥65 years.

Methods: Seven databases were searched for studies evaluating weight reduction of Food and Drug Administration (FDA)-approved AOMs. Studies had to include adults ages ≥65 years with obesity (BMI ≥ 30 kg/m or ≥27 kg/m with one weight-related condition), with independent analysis of weight reduction for adults ages ≥65 years.

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Article Synopsis
  • Deprescribing is essential for older adults, focusing on safe medication management, and effective communication is critical in this process.
  • An international group of 14 experts created a framework to analyze how communication is utilized in deprescribing, identifying the need for more comprehensive approaches beyond just clinician-patient interactions.
  • The research highlights missed opportunities for enhancing deprescribing communication at the community level and calls for further studies to determine the most effective communication strategies and styles for this process.
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Rates of specialist palliative care (SPC) vary among Veterans Affairs Medical Centers (VAMCs) for people with advanced heart failure (aHF). We evaluated the associations between facility rates of SPC reach and the quality of end of life (EOL) care received among this population. We conducted a retrospective cohort study among 3681 people with aHF who died in 83 VAMCs from 2018 to 2020.

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Article Synopsis
  • Marmoset monkeys can vocally label each other using spontaneous "phee-calls," suggesting they possess a form of vocal communication similar to that of humans, dolphins, and elephants.
  • When calls are directed specifically at them, marmosets respond more correctly, indicating a sophisticated understanding of social cues in their communication.
  • The study's findings highlight the complexity of vocalizations among nonhuman primates and suggest that marmoset calls could help researchers understand the evolution of social communication and aspects of human language.
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How do decision-makers choose between alternatives offering outcomes that are not easily quantifiable? Previous literature on decisions under uncertainty focused on alternatives with quantifiable outcomes, for example monetary lotteries. In such scenarios, decision-makers make decisions based on success chance, outcome magnitude, and individual preferences for uncertainty. It is not clear, however, how individuals construct subjective values when outcomes are not directly quantifiable.

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Article Synopsis
  • Helping older adults with many health issues can be tough because they often take lots of medications and have complicated treatment plans.
  • A study called Patient Priorities Care (PPC) aims to help by focusing on what matters most to the patients, making their healthcare experience better.
  • The study is testing this new approach with older Veterans to see if it reduces their treatment stress and improves their care based on their health priorities.
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Background: Cognitive decline may be an early indicator of major health issues in older adults, though research using population-based data is lacking. Researchers objective was to assess the relationships between distinct cognitive trajectories and subsequent health outcomes, including health status, depressive symptoms, and mortality, using a nationally representative cohort.

Methods: Data were drawn from the National Health and Aging Trends Study.

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Context: Clinical practice guidelines recommend palliative care for people with advanced heart failure (aHF), yet it remains underutilized.

Objectives: We examined medical center variation in specialist palliative care (SPC) and identified factors associated with variation among people with aHF.

Methods: We conducted a retrospective cohort study of 21,654 people with aHF who received healthcare in 83 Veterans Affairs Medical Centers (VAMCs) from 2018-2020.

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Objective: For nursing home residents with severe dementia, high-intensity medical treatment offers little possibility of benefit but has the potential to cause significant distress. Nevertheless, mechanical ventilation and intensive care unit (ICU) transfers have increased in this population. We sought to understand how and why such care is occurring.

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Objectives: Patient priorities care (PPC) is an evidence-based approach designed to help patients achieve what matters most to them by identifying their health priorities and working with clinicians to align the care they provide to the patient's priorities. This study examined the impact of the PPC approach on long-term service and support (LTSS) use among veterans.

Design: Quasi-experimental study examining differences in LTSS use between veterans exposed to PPC and propensity-matched controls not exposed to PPC adjusting for covariates.

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Article Synopsis
  • Evaluating infections in home-based primary care is complex, affecting how clinicians prescribe antibiotics and highlighting the need for improved antibiotic stewardship strategies.
  • The study involved semi-structured interviews with 22 clinicians from the Department of Veterans Affairs, exploring their experiences and decision-making regarding antibiotic use in home settings.
  • Key findings revealed that clinicians face uncertainties around diagnosing infections due to unique patient characteristics and care delivery challenges, with multiple factors influencing their decision to prescribe antibiotics, including both pressures to prescribe and concerns about potential harm.
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Study Design: This study is a retrospective cohort study.

Purpose: This study aims to determine whether preoperative neuroforaminal stenosis (FS) severity is associated with motor function patient-reported outcome measures (PROMs) following anterior cervical discectomy and fusion (ACDF).

Overview Of Literature: Cervical FS can significantly contribute to patient symptoms.

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Purpose: To examine how former caregivers for parents living with dementia engage in personal health planning.

Design: An inductive, qualitative study.

Setting: Virtual, audio-recorded, semi-structured interviews.

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Objectives: To characterize core themes conveyed by caregivers when sharing narratives of high and low caregiving points and to describe how caregivers structured these narratives.

Methods: Using consensual qualitative research and thematic analysis, high and low point narratives from 32 former caregivers of persons living with dementia were examined.

Results: High point narrative themes involved strengthening relationships with care partners, fulfillment derived from care, lighthearted moments, and fostering the care partners' joy and dignity.

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Attention-deficit/hyperactivity disorder (ADHD) is a rapidly globalizing medical category, and there is a need to attend to the on the-ground processes through which laypeople deploy the ADHD label in different local contexts. Based on in-depth interviews with Israeli mothers of children with ADHD, this article explores how mothers, as lay actors in the social field of diagnosis, interpreted the origins and meanings of their child's 'troubles'. The temporal perspective on mothers' meaning-making processes revealed a progression of four common phases through which mothers revisited their understanding of ADHD, and recast their own responsibilities and moral roles.

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Objective: To evaluate the reasons for transfer as well as the 90-day outcomes of patients who were transferred from a high-volume orthopedic specialty hospital (OSH) following elective spine surgery.

Materials And Methods: All patients admitted to a single OSH for elective spine surgery from 2014 to 2021 were retrospectively identified. Ninety-day complications, readmissions, revisions, and mortality events were collected and a 3:1 propensity match was conducted.

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Background: The measurement of specialist palliative care (SPC) across Department of Veterans Affairs (VA) facilities relies on algorithms applied to administrative databases. However, the validity of these algorithms has not been systematically assessed.

Measures: In a cohort of people with heart failure identified by ICD 9/10 codes, we validated the performance of algorithms to identify SPC consultation in administrative data and differentiate outpatient from inpatient encounters.

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Objective: To develop the architecture for a clinical decision support system (CDSS) linked to the electronic health record (EHR) using the tools provided by Research Electronic Data Capture (REDCap) to assess medication appropriateness in older adults with polypharmacy.

Materials And Methods: The tools available in REDCap were used to create the architecture for replicating a previously developed stand-alone system while overcoming its limitations.

Results: The architecture consists of data input forms, drug- and disease-mapper, rules engine, and report generator.

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Study Design: Retrospective cohort study.

Objective: To determine the impact of multiple preoperative opioid prescribers on postoperative patient opioid usage and patient-reported outcome measures after single-level lumbar fusion.

Summary Of Background Data: Prior literature has identified opioid prescriptions from multiple postoperative providers increase opioid usage rates.

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Annual prevalences of antimicrobial resistance among urine isolates (3,913 isolates and 1,736 isolates) from home-based primary care patients with dementia were high between 2014 and 2018 (ciprofloxacin, 18%-23% and 5%-7%, respectively; multidrug resistance, 9%-11% and 5%-6%, respectively). Multidrug resistance varied by region. Additional studies of antimicrobial resistance in home-care settings are needed.

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