A novel blood based triage test for colorectal cancer in primary care: a pilot study.

Background: The majority of colorectal cancers (CRCs) are detected after symptomatic presentation to primary care. Given the shared symptoms of CRC and benign disorders, it is challenging to manage the risk of missed diagnosis. Colonoscopy resources cannot keep pace with increasing demand.

Optimised Pre-Processing of Raman Spectra for Colorectal Cancer Detection Using High-Performance Computing.

Spectral pre-processing is an essential step in data analysis for biomedical diagnostic applications of Raman spectroscopy, allowing the removal of undesirable spectral contributions that could mask biological information used for diagnosis. However, due to the specificity of pre-processing for a given sample type and the vast number of potential pre-processing combinations, optimisation of pre-processing via a manual "trial and error" format is often time intensive with no guarantee that the chosen method is optimal for the sample type. Here we present the use of high-performance computing (HPC) to trial over 2.

'calling-out' vs. 'calling-in' prejudice: Confrontation style affects inferred motive and expected outcomes.

Laypersons differentiate between two confrontations styles, varying in communication style, perceived motive, and typical context: call-outs (typically public, non-accommodating language, and self-promoting confronter) and call-ins (typically private, accommodating language, and education-focused confronter). Popular press espouses a general preference for call-ins relative to call-outs, but no empirical work has addressed perceptions of these confrontation styles. To investigate the presumed efficacy of these styles, we modelled communicative differences with Communication Accommodation Theory (CAT), which explores the strategies individuals use to modulate communicative differences with interaction partners.

Model study of enhanced oil recovery by flooding with aqueous surfactant solution and comparison with theory.

With the aim of elucidating the details of enhanced oil recovery by surfactant solution flooding, we have determined the detailed behavior of model systems consisting of a packed column of calcium carbonate particles as the porous rock, n-decane as the trapped oil, and aqueous solutions of the anionic surfactant sodium bis(2-ethylhexyl) sulfosuccinate (AOT). The AOT concentration was varied from zero to above the critical aggregation concentration (cac). The salt content of the aqueous solutions was varied to give systems of widely different, post-cac oil-water interfacial tensions.