Vascular function and stiffness: population epidemiology and concordance in Australian children aged 11-12 years and their parents.

Objectives: To describe the epidemiology and parent-child concordance of vascular function in a population-based sample of Australian parent-child dyads at child age 11-12 years.

Design: Cross-sectional study (Child Health CheckPoint), nested within a prospective cohort study, the Longitudinal Study of Australian Children (LSAC).

Setting: Assessment centres in seven major Australian cities and eight regional towns or home visits, February 2015-March 2016.

Deletion of the RING-finger peroxin 2 gene in Aspergillus nidulans does not affect meiotic development.

Peroxins are required for protein import into peroxisomes as well as for peroxisome biogenesis and proliferation. Loss-of-function mutations in genes for the RING-finger peroxins Pex2, Pex10 and Pex12 lead to a specific block in meiosis in the ascomycete Podospora anserina. However, loss of protein import into peroxisomes does not result in this meiotic defect.