Therapeutic textiles: A promising approach for human skin dysbiosis?

The close interaction between skin and clothing has become an attractive cornerstone for the development of therapeutic textiles able to alleviate skin disorders, namely those correlated to microbiota dysregulation. Skin microbiota imbalance is known in several skin diseases, including atopic dermatitis (AD), psoriasis, seborrheic dermatitis, rosacea, acne and hidradenitis suppurative (HS). Such microbiota dysregulation is usually correlated with inflammation, discomfort and pruritus.

The impact of bioactive textiles on human skin microbiota.

In order to support the elevated market demand for the development of textiles with specific benefits for a healthy and safe lifestyle, several bioactive textiles with defined properties, including antimicrobial, antioxidant, anti-inflammatory, anti-odor, and anti-repellent, anti-ultraviolet (UV) radiation, have been proposed. Antimicrobial textiles, particularly, have received special interest considering the search for smart, protective textiles that also impact health and well-being. Although the incorporation of antimicrobials into textile material has been well succeeded, the addition of such components in textile clothing can influence the balance of the skin microbiota of the wearer.

Distinction of Different Colony Types by a Smart-Data-Driven Tool.

Background: Colony morphology (size, color, edge, elevation, and texture), as observed on culture media, can be used to visually discriminate different microorganisms.

Methods: This work introduces a hybrid method that combines standard pre-trained CNN keras models and classical machine-learning models for supporting colonies discrimination, developed in Petri-plates. In order to test and validate the system, images of three bacterial species (, , and ) cultured in Petri plates were used.

Probiotic Adhesion to Skin Keratinocytes and Underlying Mechanisms.

The effects of probiotics on the skin are not yet well understood. Their topical application and benefits derived thereafter have recently been investigated. Improvements in different skin disorders such as atopic dermatitis, acne, eczema, and psoriasis after their use have, however, been reported.

Image Analysis Semi-Automatic System for Colony-Forming-Unit Counting.

Background: Accurate quantitative analysis of microorganisms is recognized as an essential tool for gauging safety and quality in microbiology settings in a wide range of fields. The enumeration process of viable microorganisms via traditional culturing techniques are methodically convenient and cost-effective, conferring high applicability worldwide. However, manual counting can be time-consuming, laborious and imprecise.

Chitosan and Hydroxyapatite Based Biomaterials to Circumvent Periprosthetic Joint Infections.

Every year, worldwide, millions of people suffering from joint pain undergo joint replacement. For most patients, joint arthroplasty reduces pain and improve function, though a small fraction will experience implant failure. One of the main reasons includes prosthetic joint infection (PJI), involving the prosthesis and adjacent tissues.