Publications by authors named "Freire I"

The pursuit of artificial consciousness requires conceptual clarity to navigate its theoretical and empirical challenges. This paper introduces a composite, multilevel, and multidimensional model of consciousness as a heuristic framework to guide research in this field. Consciousness is treated as a complex phenomenon, with distinct constituents and dimensions that can be operationalized for study and for evaluating their replication.

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  • - Epilepsy is a widespread neurological disorder, with many patients suffering from drug-resistant forms where seizures persist despite medication, prompting a review of recent surgical methods for better management of the condition.
  • - The review highlighted various surgical interventions like anterior temporal lobectomy and minimally invasive techniques, which show promise in reducing seizures, as well as neuromodulation strategies for patients not eligible for traditional surgery.
  • - Despite advancements, epilepsy surgery remains underused due to challenges like inconsistent referral practices and socioeconomic barriers, emphasizing the need for better education and equitable access to improve patient outcomes.
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  • The study aimed to establish normative ADC values for the pineal gland in children aged 0-4, which can assist in diagnosing conditions like trilateral retinoblastoma, particularly when tumors are small.
  • Researchers analyzed MRI data from 64 children with normal findings, calculating gland size and ADC values while grouping them by age.
  • Results showed that normal ADC values were significantly higher than those found in patients with trilateral retinoblastoma, indicating that DWI/ADC could be useful in identifying small tumors in young children.
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This study analyzes the life stories of eight young people living with vertically transmitted HIV in order to understand their perceptions marked by secrecy and silence regarding their experiences with the virus. Conducted at a specialized outpatient clinic in Rio de Janeiro, the study adopted circle dance, a Complementary and Integrative Health Practice, as a care tool. Using a qualitative approach and Life History as a data collection method, the focus was to understand the youth's experiences related to the disease and the crucial aspects of their lives.

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The two-component regulatory system CenK-CenR has recently emerged as a regulator of cell envelope and cell division processes in the alpha-proteobacteria. In Sinorhizobium meliloti, CenK-CenR regulates the expression of SrlA, a thioredoxin-domain protein of unknown function. Deletion of srlA causes sensitivity to salt and oxidizing agents on solid growth medium.

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This paper introduces DAC-HRC, a novel cognitive architecture designed to optimize human-robot collaboration (HRC) in industrial settings, particularly within the context of Industry 4.0. The architecture is grounded in the Distributed Adaptive Control theory and the principles of joint intentionality and interdependence, which are key to effective HRC.

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This article analyzes practices of care and the HIV diagnosis disclosure process to children and adolescents living with HIV/AIDS. A case study was conducted in an outpatient clinic located in a public hospital in Rio de Janeiro through participant observation, semi-structured interviews with health professionals, and the consultation of documents produced by the professionals. The analysis, based on the sociology of Simmel and Goffman, points to the revelation of the diagnosis as a hallmark that accompanies all the care established with users and sheds light on issues such as secrecy, stigma and the possible understandings about the health condition established.

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Introduction: Sensory systems provide the necessary information for a motor response to be provided. In this sense, the objective of this study is to evaluate the effectiveness of a sensorimotor exercise program on proprioceptive acuity, balance, muscle strength, functional mobility and risk of falls in institutionalized elderly.

Methodology: 56 participants (84.

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Dapagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2i), has shown demonstrated benefits for renal and cardiovascular outcomes in large clinical trials. However, short-term concerns regarding its impact on renal function and electrolyte balance exist. This study aimed to evaluate the short-term effects of dapagliflozin on renal function and electrolyte balance in patients newly prescribed the medication.

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Introduction: Diffusion tensor imaging (DTI) is a valuable non-invasive imaging modality for mapping white matter tracts and assessing microstructural integrity, and can be used as a "biomarker" in diagnosis, differentiation, and therapeutic monitoring. Although it has gained clinical importance as a marker of neuropathology, limitations in its interpretation underscore the need for caution.

Methods: This review provides an overview of the principles and clinical applicability of DTI.

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Spontaneous spine epidural haematoma is a rare occurrence, with an incidence of 0.1/100 000 inhabitants/year. The anterior location of the haematoma is very uncommon since the dural sac is firmly attached to the posterior longitudinal ligament.

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In patients with ischaemic stroke, a carotid free-floating thrombus (CFFT) raises diagnostic and therapeutic challenges. We describe two women, each taking tamoxifen for invasive non-metastatic breast cancer, who developed large-vessel occlusion ischaemic strokes. The first had a CFFT 24 hours after receiving intravenous thrombolysis and mechanical thrombectomy; the thrombus completely resolved after 1 week of therapeutic anticoagulation.

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Several potential risk factors have been identified in the etiopathogenesis of febrile seizures (FS), including the type and extent of breastfeeding (BF). Given the lack of conclusive data, this study aims to systematically evaluate the evidence on the association between BF and FS. We conducted a systematic review and meta-analysis according to PRISMA guidelines.

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Living systems ensure their fitness by self-regulating. The optimal matching of their behavior to the opportunities and demands of the ever-changing natural environment is crucial for satisfying physiological and cognitive needs. Although homeostasis has explained how organisms maintain their internal states within a desirable range, the problem of orchestrating different homeostatic systems has not been fully explained yet.

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  • The study identified a new gene in a nitrogen-fixing bacterial symbiont that is essential for growth in high salt environments and shows increased sensitivity to oxidative stress.
  • The gene, named stress resistance locus A (srlA), encodes a protein with a thioredoxin fold, and its deletion led to interesting genetic revertants that altered the bacterial response to stress.
  • Additionally, the research revealed that the srlA promoter is autoregulated and requires specific sequence elements for high activity, while a response regulator protein (CenR) likely acts as a Class II activator influencing the transcription of srlA under stress conditions.
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Introduction: Insomnia is a common sleep disorder in elderly. Although the HIV-positive population have a similar life expectancy when compared to the general population, some factors may interact with immunity conditions and therefore contribute to a worse prognosis.

Objective: This is a review of literature that aims to identify prevalence of insomnia in older HIV-positive patients.

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The article focuses on the experience of family and social frailty of children with congenital Zika virus syndrome (CZVS) and discusses the changes in support networks, in the sense of both their capacities and shortcomings. This qualitative study adopted a clinical-psychosociological approach. The study analyzed family narratives in 32 group meetings conducted in an outpatient setting in a referral research institute for CZVS care in the State of Rio de Janeiro, Brazil.

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The relationship between the Renin-Angiotensin-Aldosterone System (RAAS) and modulation of the Autonomic Nervous System (ANS) is reported as complex and bidirectional. Thus, the present study aimed to compare autonomous heart control, through symbolic analysis parameters, in the older adults carrying different ACE I/D gene polymorphisms (rs4646994). Two hundred four older adults comprised the study population and were grouped according to the ACE I/D gene polymorphism: II + ID genotype and DD genotype.

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Purpose: This study aimed to compare heart rate variability (HRV) parameters obtained through symbolic analysis (SA), between older adults with and without hyperuricemia.

Methods: This is a cross-sectional study including 202 community-dwelling old adults, which was clinically stratified as with or without hyperuricemia, according to the cutoff point of serum uric acid ≥ 6 mg/dL for women and ≥ 7 mg/dL for men. Successive RR intervals were recorded along 5 min and analyzed with SA method.

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What is the role of real-time control and learning in the formation of social conventions? To answer this question, we propose a computational model that matches human behavioral data in a social decision-making game that was analyzed both in discrete-time and continuous-time setups. Furthermore, unlike previous approaches, our model takes into account the role of sensorimotor control loops in embodied decision-making scenarios. For this purpose, we introduce the Control-based Reinforcement Learning (CRL) model.

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The nutritional value of the marine cryptophyte Rhodomonas lens for the filter feeder Brachionus plicatilis as well as its biotechnological potential as a source of phycoerythrin (PE) and polyunsaturated fatty acids (PUFA) were evaluated in semi-continuous cultures maintained with different daily renewal rates (RR), from 10% (R10) to 50% (R50) of the total volume. Steady-state cell density decreased from 22 to 7 × 10 cells mL with increasing RR, with the maximum cell productivity, nearly 0.4 g L day, observed with R40.

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  • The study investigates the influence of bacteria acquired post-brooding on the development of planula-larvae for the octocoral Rhytisma f. fulvum, using various types of seawater in a lab setting.* -
  • Results showed successful larval metamorphosis (60-80%) even in bacteria-free conditions, suggesting that bacteria obtained during brooding are sufficient for development, but autoclaving seawater negatively affected development.* -
  • Light exposure positively influenced larval growth after 20 days, hinting at either the role of light as a developmental cue or potential beneficial phototrophic bacteria, highlighting the importance of bacterial interactions in coral biology.*
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The Neotropical genus Aparasphenodon Miranda-Ribeiro is composed of five recognized species commonly referred as "casque-headed frogs" (Frost 2018). Aparasphenodon brunoi Miranda-Ribeiro occurs in Atlantic Forest lowlands from the states of São Paulo to Bahia, Brazil (Feio et al. 1998; Mollo Neto Teixeira Jr.

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This article aims to discuss the impacts of the promotion of families' mental health following the diagnosis of Zika virus infection in the pregnant woman and/or congenital Zika virus syndrome (CZVS) in the infant. The study also aims to foster reflection on mother-infant bonding in this context. The study is relevant not only because there is still so much to learn about CZVS, with its enormous capacity for dispersion and many doubts as to the physical consequences and psychological impacts, but also due to the urgent need to provide families and/or caregivers with guidelines for care and alternatives for dealing with the illness.

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