Thermoelectric Performance of Tetrahedrite (CuSbS) Thin Films: The Influence of the Substrate and Interlayer.

In the present work, tetrahedrite CuSbS thin films were deposited on various substrates via aerosol-assisted chemical vapor deposition (AACVD) using diethyldithiocarbamate complexes as precursors. A buffer layer of SbO with a small lattice mismatch to CuSbS was applied to one of the glass substrates to improve the quality of the deposited thin film. The buffer layer increased the coverage of the CuSbS thin film, resulting in improved electrical transport properties.

Exceptional Thermoelectric Performance of Cu(Zn,Fe,Cd)SnS Thin Films.

High-quality Cu(Zn,Fe,Cd)SnS (CZFCTS) thin films based on the parent CZTS were prepared by aerosol-assisted chemical vapor deposition (AACVD). Substitution of Zn by Fe and Cd significantly improved the electrical transport properties, and monophasic CZFCTS thin films exhibited a maximum power factor (PF) of ∼0.22 μW cm K at 575 K.

Family screening for bicuspid aortic valve and aortic dilatation: a meta-analysis.

Aims: International guidelines recommend screening of first-degree relatives (FDR) of people with bicuspid aortic valves (BAVs). However, the prevalence of BAV and of aortic dilatation amongst family members is uncertain.

Methods And Results: A systematic review and meta-analysis of original reports of screening for BAV.

Enhanced Thermoelectric Performance of Tin(II) Sulfide Thin Films Prepared by Aerosol Assisted Chemical Vapor Deposition.

Orthorhombic SnS exhibits excellent thermoelectric performance as a consequence its relatively high Seebeck coefficient and low thermal conductivity. In the present work, polycrystalline orthorhombic SnS thin films were prepared by aerosol-assisted chemical vapor deposition (AACVD) using the single source precursor dibutyl-(diethyldithiocarbamato)tin(IV) [Sn(CH)(SCN(CH))]. We examined the effects of the processing parameters on the composition, microstructure, and electrical transport properties of the SnS films.

Clinical support during COVID-19: An opportunity for service and learning? A cross-sectional survey of UK medical students.

Purpose: Medical students providing support to clinical teams during Covid-19 may have been an opportunity for service and learning. We aimed to understand why the reported educational impact has been mixed to inform future placements.

Methods: We conducted a cross-sectional survey of medical students at UK medical schools during the first Covid-19 'lockdown' period in the UK (March-July 2020).

Precursor-Led Grain Boundary Engineering for Superior Thermoelectric Performance in Niobium Strontium Titanate.

We present a novel method to significantly enhance the thermoelectric performance of ceramics in the model system SrTiNbO through the use of the precursor ammonium tetrathiomolybdate (0.5-2% w/w additions). After sintering the precursor-infused green body at 1700 K for 24 h in 5% H/Ar, single-crystal-like electron transport behavior developed with electrical conductivity reaching ∼3000 S/cm at ∼300 K, almost a magnitude higher than that in the control sample.

High Power Factor Nb-Doped TiO Thermoelectric Thick Films: Toward Atomic Scale Defect Engineering of Crystallographic Shear Structures.

Donor-doped TiO-based materials are promising thermoelectrics (TEs) due to their low cost and high stability at elevated temperatures. Herein, high-performance Nb-doped TiO thick films are fabricated by facile and scalable screen-printing techniques. Enhanced TE performance has been achieved by forming high-density crystallographic shear (CS) structures.

Controlling the Thermoelectric Behavior of La-Doped SrTiO through Processing and Addition of Graphene Oxide.

The addition of graphene has been reported as a potential route to enhance the thermoelectric performance of SrTiO. However, the interplay between processing parameters and graphene addition complicates understanding this enhancement. Herein, we examine the effects of processing parameters and graphene addition on the thermoelectric performance of La-doped SrTiO (LSTO).

Tin-Substituted Chalcopyrite: An -Type Sulfide with Enhanced Thermoelectric Performance.

The dearth of -type sulfides with thermoelectric performance comparable to that of their type analogues presents a problem in the fabrication of all-sulfide devices. Chalcopyrite (CuFeS) offers a rare example of an -type sulfide. Chemical substitution has been used to enhance the thermoelectric performance of chalcopyrite through preparation of Cu Sn FeS (0 ≤ ≤ 0.

Controlling the Thermoelectric Properties of Nb-Doped TiO Ceramics through Engineering Defect Structures.

Donor-doped TiO ceramics are promising high-temperature oxide thermoelectrics. Highly dense (1 - )TiO-NbO (0.005 ≤ ≤ 0.

Modulation of Charge Transport at Grain Boundaries in SrTiO: Toward a High Thermoelectric Power Factor at Room Temperature.

Modulation of the grain boundary properties in thermoelectric materials that have thermally activated electrical conductivity is crucial in order to achieve high performance at low temperatures. In this work, we show directly that the modulation of the potential barrier at the grain boundaries in perovskite SrTiO changes the low-temperature dependency of the bulk material's electrical conductivity. By sintering samples in a reducing environment of increasing strength, we produced LaSrTiO (LSTO) ceramics that gradually change their electrical conductivity behavior from thermally activated to single-crystal-like, with only minor variations in the Seebeck coefficient.

An assessment of adherence to CARE reporting standards by case reports published in in 2018.

Background: Case reports are subject to significant variation in their content, and the absence of pertinent case details can limit their benefit to the medical community. To aid this, a reporting standard (CARE) has been developed. Case reports published in () are subject to specific checks by editors to confirm compliance with the CARE reporting standard.

Enhancing the Thermoelectric Performance of Calcium Cobaltite Ceramics by Tuning Composition and Processing.

Calcium cobaltite (CaCoO) is a promising p-type thermoelectric oxide material. Here, we present an approach to optimize the thermoelectric performance of CaCoO by controlling the chemical composition and fabrication process. CaBiCoO (0.

Supersaturated proteins are enriched at synapses and underlie cell and tissue vulnerability in Alzheimer's disease.

Neurodegenerative disorders progress across the brain in characteristic spatio-temporal patterns. A better understanding of the factors underlying the specific cell and tissue vulnerability responsible for such patterns could help identify the molecular origins of these conditions. To investigate these factors, based on the observation that neurodegenerative disorders are closely associated with the presence of aberrant protein deposits, we made the hypothesis that the vulnerability of cells and tissues is associated to the overall levels of supersaturated proteins, which are those most metastable against aggregation.

Self-Nanostructuring in SrTiO: A Novel Strategy for Enhancement of Thermoelectric Response in Oxides.

Nanostructuring is recognized as an efficient route for enhancing thermoelectric response. Here, we report a new synthesis strategy for nanostructuring oxide ceramics and demonstrate its effectiveness on an important n-type thermoelectric SrTiO. Ceramics of SrLaTiO with additions of BO were synthesized by the mixed oxide route.

Enhancing the thermoelectric properties of SrPr□ TiO through control of crystal structure and microstructure.

A-site deficient perovskites are among the most important n-type thermoelectric oxides. Ceramics of SrPr□ TiO ( x = 0.1-1.

A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.

Excitatory neurons are preferentially impaired in early Alzheimer's disease but the pathways contributing to their relative vulnerability remain largely unknown. Here we report that pathological tau accumulation takes place predominantly in excitatory neurons compared to inhibitory neurons, not only in the entorhinal cortex, a brain region affected in early Alzheimer's disease, but also in areas affected later by the disease. By analyzing RNA transcripts from single-nucleus RNA datasets, we identified a specific tau homeostasis signature of genes differentially expressed in excitatory compared to inhibitory neurons.

Managing dose-, damage- and data-rates in multi-frame spectrum-imaging.

As an instrument, the scanning transmission electron microscope is unique in being able to simultaneously explore both local structural and chemical variations in materials at the atomic scale. This is made possible as both types of data are acquired serially, originating simultaneously from sample interactions with a sharply focused electron probe. Unfortunately, such scanned data can be distorted by environmental factors, though recently fast-scanned multi-frame imaging approaches have been shown to mitigate these effects.

Prospects for Engineering Thermoelectric Properties in LaNbO Ceramics Revealed via Atomic-Level Characterization and Modeling.

A combination of experimental and computational techniques has been employed to explore the crystal structure and thermoelectric properties of A-site-deficient perovskite LaNbO ceramics. Crystallographic data from X-ray and electron diffraction confirmed that the room temperature structure is orthorhombic with Cmmm as a space group. Atomically resolved imaging and analysis showed that there are two distinct A sites: one is occupied with La and vacancies, and the second site is fully unoccupied.

Concurrent La and A-Site Vacancy Doping Modulates the Thermoelectric Response of SrTiO: Experimental and Computational Evidence.

To help understand the factors controlling the performance of one of the most promising n-type oxide thermoelectric SrTiO, we need to explore structural control at the atomic level. In SrLaTiO ceramics (0.0 ≤ x ≤ 0.

gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development.

Low nephron endowment at birth has been associated with an increased risk for developing hypertension and chronic kidney disease. We demonstrated in an earlier study that conditional deletion of the microRNA (miRNA)-processing enzyme Dicer from nephron progenitors results in premature depletion of the progenitors and increased expression of the proapoptotic protein Bim (also known as Bcl-2L11). In this study, we generated a compound mouse model with conditional deletion of both and , to determine the biologic significance of increased Bim expression in -deficient nephron progenitors.

Tuning the thermoelectric properties of A-site deficient SrTiO ceramics by vacancies and carrier concentration.

Ceramics based on SrLaTiNbO have been prepared by the mixed oxide route. The LaNbO component generates ∼13.4% A-site vacancies; this was fixed for all samples.

A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer's disease.

In Alzheimer's disease, aggregates of Aβ and tau in amyloid plaques and neurofibrillary tangles spread progressively across brain tissues following a characteristic pattern, implying a tissue-specific vulnerability to the disease. We report a transcriptional analysis of healthy brains and identify an expression signature that predicts-at ages well before the typical onset-the tissue-specific progression of the disease. We obtain this result by finding a quantitative correlation between the histopathological staging of the disease and the expression patterns of the proteins that coaggregate in amyloid plaques and neurofibrillary tangles, together with those of the protein homeostasis components that regulate Aβ and tau.