Antimicrob Agents Chemother
November 2024
The cefazolin inoculum effect (CzIE) has been associated with poor clinical outcomes in patients with methicillin-susceptible (MSSA) infections. We aimed to investigate the point prevalence of the CzIE among nasal colonizing MSSA isolates from ICU patients in a multicenter study in Colombia (2019-2023). Patients underwent nasal swabs to assess for colonization on admission to the ICU, and some individuals had follow-up swabs.
View Article and Find Full Text PDFmedRxiv
July 2024
The cefazolin inoculum effect (CzIE) has been associated with poor clinical outcomes in patients with MSSA infections. We aimed to investigate the point prevalence of the CzIE among nasal colonizing MSSA isolates from ICU patients in a multicenter study in Colombia (2019-2023). Patients underwent nasal swabs to assess for colonization on admission to the ICU and some individuals had follow-up swabs.
View Article and Find Full Text PDFMicroorganisms
January 2023
Patients with cancer have a higher risk of severe bacterial infections. This study aims to determine the frequency, susceptibility profiles, and resistance genes of bacterial species involved in bacteremia, as well as risk factors associated with mortality in cancer patients in Colombia. In this prospective multicenter cohort study of adult patients with cancer and bacteremia, susceptibility testing was performed and selected resistance genes were identified.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
March 2023
Climate change might affect energy production and therefore the energy security of a country or region. This situation may impact renewable energy sources such as hydro power, leading to consequences on energy transition strategies. This might be critical in sensitive regions to climate change, one of them being the Caribe and northern South America.
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