Publications by authors named "Fredrick Were"

The study examined nurse characteristics associated with Knowledge, Attitudes, and Practices (KAP) regarding malaria vaccination in Bungoma County, Kenya. Malaria remains a major health burden in Kenya, with 3.4 million cases and 12,000 deaths in 2021.

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Article Synopsis
  • - Children and adolescents with HIV (CAHIV) face a higher risk of chronic lung disease (CLD) due to recurrent respiratory issues, and with better access to antiretroviral therapy, there's an increasing need for long-term care in these patients, particularly in African countries like Kenya.
  • - A study involving 320 CAHIV in Nairobi explored the prevalence of CLD, finding that 26% showed signs of respiratory issues, with common symptoms including breathlessness, chronic cough, and exercise limitations.
  • - Key factors associated with CLD included prior pneumonia or tuberculosis, younger age at ART initiation, living conditions, and environmental factors, highlighting the need for targeted care and interventions for these patients.
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Background: Emerging evidence suggests that after completion of treatment for tuberculosis (TB) a significant proportion of patients experience sequelae. However, there is limited synthesized evidence on this from low-income countries, from Sub-Saharan Africa, and in HIV infected individuals. We seek to provide an updated comprehensive systematic review and meta-analysis on the magnitude and factors associated with post-TB lung disease (PTLD) in low- and middle-income countries (LMICs).

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Background: Postnatal depression (PND) is a universal mental health problem that prevents mothers' optimal existence and mothering. Although research has shown high PND prevalence rates in Africa, including Kenya, little research has been conducted to determine the contributing factors, especially in low-resource communities.

Objective: This study aimed to investigate the PND risk factors among mothers attending Lang'ata and Riruta Maternal and Child Health Clinics (MCH) in the slums, Nairobi.

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Objectives: Prematurity is the leading cause of global neonatal and infant mortality. Many babies could survive by the provision of essential newborn care. This qualitative study was conducted in order to understand, from a family and professional perspective, the barriers and facilitators to essential newborn care.

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Objective: To evaluate the association between obstetric and medical risk factors and stillbirths in a Kenyan set-up.

Methods: A case-control study was conducted in four hospitals between August 2018 and April 2019. Two hundred and fourteen women with stillbirths and 428 with live births at more than >28 weeks of gestation were enrolled.

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Research has shown that postnatal depression (PND) is higher in low- and middle-income countries as compared to higher-income countries. Despite this, little is known about practical interventions in these poorly resourced countries. This research investigated the effectiveness of a brief, prophylactic and therapeutic psychoeducational intervention in a low-resourced community in Nairobi.

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Introduction: Fifteen million babies are born prematurely, before 37 weeks gestational age, globally. More than 80% of these are in sub-Saharan Africa and Asia. 35% of all deaths in the first month of life are due to prematurity and the neonatal mortality rate is eight times higher in low-income and middle-income countries (LMICs) than in Europe.

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Background: The safety and efficacy of antenatal glucocorticoids in women in low-resource countries who are at risk for preterm birth are uncertain.

Methods: We conducted a multicountry, randomized trial involving pregnant women between 26 weeks 0 days and 33 weeks 6 days of gestation who were at risk for preterm birth. The participants were assigned to intramuscular dexamethasone or identical placebo.

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Introduction: About 2.6 million stillbirths per year occur globally with 98% occurring in low- and middle-income countries including Kenya, where an estimated 35 000 stillbirths occur annually. Most studies have focused on the direct causes of stillbirth.

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Introduction: Africa bears the greatest burden of stillbirth and yet, there is a paucity of data from this setting. The aim of this study was to determine the association between quality of intrapartum care and fresh stillbirth in Nairobi, Kenya.

Methods And Materials: This was a case control study in 4 tertiary public hospitals in Nairobi county from August 2018 to April 2019.

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Achieving high and equitable childhood immunisation coverage in Africa will not only protect children from disability and premature death, it will also boost productivity, reduce poverty and support the economic growth of the continent. Thus, Africa needs innovative and sustainable vaccine advocacy initiatives. One such initiative is the African Vaccine-Preventable Diseases Network, formed in 2009.

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