Publications by authors named "Fredrick N Southern"
Objective: The purpose of this study was to determine the effects of dichloroacetate (DCA) in acute limb ischemia.
Methods: Anterior tibialis muscle samples of DCA-treated and control animals (Sprague Dawley rats) were collected and assayed for pyruvate dehydrogenase activity, lactate, adenosine triphosphate, and creatine phosphate using spectrophotometry. A physiograph was used to measure fatigability.