Publications by authors named "Fredrick C Otieno"
Article Synopsis
- Systemic inflammation is a key predictor of cardiovascular disease (CVD) risk, showing a 2-fold increase among individuals living with HIV (PLHIV).
- A study in Kenya measured inflammatory markers in both PLHIV and HIV-negative individuals, finding significantly higher levels of markers like IL-6 and TNF-α in those with HIV, regardless of other CVD risk factors.
- The findings suggest that even virally suppressed PLHIV have elevated inflammation levels, indicating the need for further research to explore the predictive value of these markers for future CVD events and potential treatments.
To determine the prevalence and correlates of metabolic syndrome (MetS) and compare 10-year cardiovascular disease (CVD) risk among Kenyan adults with and without HIV infection.We conducted a cross-sectional study among adults ≥30 years of age with and without HIV infection seeking care at Kisumu County Hospital. Participants completed a health questionnaire and vital signs, anthropomorphic measurements, and fasting blood were obtained.
View Article and Find Full Text PDFBackground: Health care systems in sub-Saharan Africa, and globally, grapple with the problem of closing the gap between evidence-based health interventions and actual practice in health service settings. It is essential for health care systems, especially in low-resource settings, to increase capacity to implement evidence-based practices, by training professionals in implementation science. With support from the Medical Education Partnership Initiative, the University of Nairobi has developed a training program to build local capacity for implementation science.
View Article and Find Full Text PDF