Publications by authors named "Frederique Pavillard"

Article Synopsis
  • * In a cohort of 277 patients, the new strategy significantly reduced the occurrence of delayed cerebral infarction (DCIn) and improved early detection of vasospasm-related complications.
  • * The findings suggest that using CT perfusion to guide milrinone administration can effectively prevent and treat DCIn, showing promise for improving patient outcomes after aSAH.
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Background: Early Mobilization in Intensive Care Units (ICUs) enhances patients' evolution, but has been rarely studied in neurological ICUs. The aim of this study was to assess gait training with body-weight support (BWS) in neuroICU, and to report on its safety, feasibility and on delays before walking with and without BWS.

Methods: This study was an observational one-year single-center study.

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Purpose: The relationship between posterior-circulation lesion volume (PCLV) and clinical outcomes is poorly investigated. We aimed to analyze, in patients with acute basilar artery occlusion (ABAO), if pre-endovascular treatment (EVT) PCLV was a predictor of outcomes.

Methods: We analyzed consecutive MRI selected, endovascularly treated ABAO patients.

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Article Synopsis
  • The study evaluated the use of transcranial sonography (TCS) for measuring the diameter of the third ventricle (V3) in brain-injured patients and compared its reliability with brain CT scans, finding a strong correlation between the two methods.
  • In a sample of 100 ICU patients, V3 measurements were successfully taken in 87%, and the TCS results were able to detect hydrocephalus in about 89% of cases where it could be assessed.
  • The study also showed that residents could achieve reliable TCS measurements after performing just five procedures, indicating a quick learning curve for this technique.
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Background: Patients affected with aneurysmal subarachnoid hemorrhage (aSAH) often require intensive care, and then present distinctive outcome from less severe patients. We aimed to specify their long-term outcome and to identify factors associated with poor outcome.

Methods: We conducted a retrospective study in a French university hospital intensive care unit.

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Background: Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who have undergone endovascular treatment (EVT) remain controversial. Our aim was to determine if pre-EVT diffusion-weighted imaging cerebellar infarct volume (CIV) is a predictor of 90-day outcomes.

Methods: We analyzed consecutive MRI-selected endovascularly treated patients with ABAO within the first 24 hours after symptom onset.

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Article Synopsis
  • Heterozygous mutations in the KMT2B gene are linked to early-onset dystonia (DYT28), featuring motor problems that start locally and can spread throughout the body, particularly affecting the face and neck.
  • A study of 53 patients with KMT2B mutations revealed new disease presentations and identified various health issues, such as growth retardation and endocrine disorders, as well as a higher impact on patients with more severe genetic variants.
  • Patients who underwent deep brain stimulation for severe dystonia showed significant improvement in motor function and disability over time, with more than half experiencing over 30% improvement at the one-year mark.
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Optimal management of intracranial pressure (ICP) among aneurysmal subarachnoid hemorrhage (aSAH) patients requiring external ventricular drainage (EVD) is controversial. To analyze predictors of delayed cerebral ischemia (DCI)-related cerebral infarction after aSAH and the influence of ICP values on DCI, we prospectively collected consecutive patients with aSAH receiving coiling and requiring EVD. Predictors of DCI-related cerebral infarction (new CT hypodensities developed within the first 3 weeks not related to other causes) were studied.

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